Background: In developed countries, increasing food allergy prevalence and concern regarding food allergies have been reported. Although the use of complementary and alternative medicine (CAM) for the treatment of allergic diseases has increased in some Western countries, the actual proportion and patterns of CAM use for pediatric food allergies in Japan are still unknown. Methods: Fourteen allergy centers in Japan participated in the study using a questionnaire survey regarding the use of CAM by pediatric patients. A diagnosis of food allergy was made at each hospital by pediatric allergists. Results: Surveys were completed by parents/guardians, and data were collected for a total of 962 pediatric food-allergic patients. Overall, 8.4% of the participants used CAM to treat a food allergy. The major CAM therapies used were herbal teas (22.2%), including several Japanese herbal teas, Chinese herbal medicine (18.5%) and lactic acid bacteria (16%). Among the participants using CAM to treat food allergy, 13.6% thought that the CAM being used was very effective, while 11.1% of participants thought that CAM caused some type of side effect. Conclusions: Our study is the first large-scale national survey regarding the use of CAM in pediatric patients with food allergies in Japan. Unlike in the USA, which has a higher rate of CAM use (17%), approximately 8.4% of food-allergic patients used CAM in Japan. Interestingly, the major types of CAM used in Japan differed from those used in the USA. Cultural differences and food customs may affect the use of CAM.

Keywords:
Food allergy, Complementary and alternative medicine
1.
Sicherer SH, Sampson HA: Peanut allergy: emerging concepts and approaches for an apparent epidemic. J Allergy Clin Immunol 2007;120:491–503.
2.
Keil T: Epidemiology of food allergy: what’s new? A critical appraisal of recent population-based studies. Curr Opin Allergy Clin Immunol 2007;7:259–263.
3.
Venter C, Pereira B, Voigt K, Grundy J, Clayton CB, Higgins B, Arshad SH, Dean T: Original article: prevalence and cumulative incidence of food hypersensitivity in the first 3 years of life. Allergy 2008;63:354–359.
4.
Venter C, Pereira B, Grundy J, Clayton CB, Arshad SH, Dean T: Prevalence of sensitization reported and objectively assessed food hypersensitivity amongst six-year-old children: a population-based study. Pediatr Allergy Immunol 2006;17:356–363.
5.
Ebisawa M: Management of food allergy in Japan ‘Food Allergy Management Guideline 2008 (revision from 2005)’ and ‘Guidelines for the Treatment of Allergic Diseases in Schools’. Allergol Int 2009;58:475–483.
6.
Keet CA, Matsui EC, Dhillon G, Lenehan P, Paterakis M, Wood RA: The natural history of wheat allergy. Ann Allergy Asthma Immunol 2009;102:410–415.
7.
Skripak JM, Matsui EC, Mudd K, Wood RA: The natural history of IgE-mediated cow’s milk allergy. J Allergy Clin Immunol 2007;120:1172–1177.
8.
Savage JH, Matsui EC, Skripak JM, Wood RA: The natural history of egg allergy. J Allergy Clin Immunol 2007;120:1413–1417.
9.
Eisenberger D, Davis R, Ettner S, Appel S, Wilkey S, Van Rompay M: Trends in alternative medicine in the United States 1990–1997. JAMA 1998;18:1569–1575.
10.
Slader C, Reddel H, Jenkins C, Armour C, Bosnic-Anticevich S: Complementary and alternative medicine use in asthma: who is using what? Respirology 2006;11:373–387.
11.
Ko J, Lee J, Muñoz-Furlong A, Li X, Sicherer S: Use of complementary and alternative medicine by food-allergic patients. Ann Allergy Asthma Immunol 2006;97:365–369.
12.
Mark J: Integrative medicine and asthma. Pediatr Clin North Am 2007;54:1007–1023.
13.
Li X: Complementary and alternative medicine in pediatric allergic disorders. Curr Opin Allergy Clin Immunol 2009;9:161–167.
14.
Niggemann B, Grüber C: Side-effects of complementary and alternative medicine. Allergy 2003;58:707–716.
15.
Ernst E: Adverse effects of herbal drugs in dermatology. Br J Dermatol 2000;143:923–929.
16.
Ernst E: Harmless herbs? A review of the recent literature. Am J Med 1998;104:170–178.
17.
Nornheim A: Adverse effects of acupuncture: a study of the literature for the years 1981–1994. J Altern Complement Med 1996;2:291–297.
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2012
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