... to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Endocrine disruptor Androgen receptor Polymorphism [email protected] 24 11 2015 28 12 2015 2 2 2016 Ailments of the reproductive...

... cells. The aim of this study was to evaluate the association between GPR30 single nucleotide polymorphisms and gynecomastia in males. Methods: This study included 109 male adolescents with gynecomastia and 104 controls. Follicle stimulating hormone, luteinizing hormone, total testosterone, estradiol (E2...

...Eva Landmann; Barbara Kollerits; Joachim Gerhard Kreuder; Werner Friedrich Blum; Florian Kronenberg; Silvia Rudloff Background/Aims: In postnatal life, polymorphisms in the promoter region of IGFBP3 were associated with insulin-like growth factor binding protein (IGFBP)-3 plasma levels. Whether...

... insulin dosing of 567 patients, we selected 177 for whom we also had genome-wide genotyping data. Using PLINK software, we examined the association between insulin requirement as a quantitative trait and nineteen T2D risk loci. Results: Out of 19 single-nucleotide polymorphisms (SNPs), rs13266634...

... SD. We genotyped 10 common polymorphisms previously associated with height variation. Results: The HMGA2 gene SNP was significantly associated with tall stature. Using a logistic regression model, we calculated that carrying the HMGA2 (rs1042725) C allele significantly increased the odds of being...

... controls in a case-control study of ovarian cancer [ 11 ]. The Val660Leu variant was also significantly associated with spontaneous abortion in a case-control study [ 12 ]. No studies were identified that examined the association between progesterone receptor polymorphisms and age at menarche. Because...

...Soo Heon Kwak; Tae Hyuk Kim; Young Min Cho; Sung Hee Choi; Hak C. Jang; Kyong Soo Park Background: Recent genome-wide association studies in East Asians have identified polymorphisms in KCNQ1 as new type 2 diabetes risk variants. The aim of this study was to investigate whether variants in KCNQ1...

... (HSD11B1), which converts inactive cortisone to active cortisol, has become an emerging therapeutic target for type 2 diabetes mellitus and obesity. In this study, we examined the association between HSD11B1 polymorphisms and type 2 diabetes and metabolic phenotypes in Koreans. Methods: We sequenced all...

... therapy. The GH receptor (GHR) is the first key molecule mediating GH action. In the past 3 years, a common GHR polymorphism reflecting the presence ( GHR fl) or absence ( GHR d3) of exon 3 has been under intensive investigation regarding its influence on the response to hGH therapy. Studies...

... polymorphism (PCR-SSCP). We could not detect any alterations of type II 3β-HSD gene from these patients. Our result strongly suggests that unlike classical 3β-HSD deficiency, NC3β-HSD deficiency may be secondary adrenal biosynthetic defects, rather than dual inherited deficiencies. 18 09 1995 26 04...

... polymorphism (RFLP) in normotensive and hypertensive subjects without (HTG-) and with a genetic predisposition to essential hypertension (HTG+). The frequency of the 9.0-kb fragment was significantly (p < 0.05) higher in the HTG+ group than in the normotensive and HTG- groups. An association between renin...

... transcription polymerase chain reaction/single-strand conformation polymorphism methods. OT gene expression in the cumulus cells was positive in 5 women and weakly positive in the remaining patient. The structure of OT mRNA in the cumulus cells was equivalent to that in human hypothalamus. OTR gene expression...

... responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Blood pressure Genes Glucose Insulin Obesity Polymorphism Transforming growth factor Transforming growth factor (TGF)-β 1...

... Over 99.9% of the DNA sequence is identical between any two individuals [ 5 ]. The approximately 0.1% that differs must be responsible for genetically determined individual traits, including disease susceptibility. Most of this variation is the result of common DNA variants (polymorphisms), of which...