... has increased over decades. We evaluated whether the increased LT4 dosing influenced thyroid-stimulating hormone (TSH) and thyroxine (fT4) concentrations, growth, or treatment-related symptoms. Methods: LT4 doses, TSH, fT4, anthropometrics, and treatment-related symptoms until age 2 years were...

... thyroxine (fT4), body mass index standard deviation scores (BMI SDS), as well as variables of lipid and glucose metabolism were examined. Results: Children with high-normal TSH (>3.0 mU/L) (28.8%) had higher BMI SDS compared to children with low-normal TSH (<3.0 mU/L) ( p < 0.001). Multivariable...

... due to iodine deficiency. We aimed to determine whether it is beneficial to administer iodine supplementation in addition to the L -thyroxine ( L -T 4 ) treatment of newborns with congenital hypothyroidism due to iodine deficiency. Materials and Methods: Of 51 newborns, 26 who were diagnosed...

... hypothesized that Down syndrome was associated with fetal hypothyroidism and tried to determine whether Down syndrome fetuses had evidence of hypothyroidism. Methods: We performed a prospective observational study on 13 fetuses with Down syndrome diagnosed prenatally. TSH and free thyroxine (FT4) levels were...

...V. Scarpa; E. Kousta; A. Tertipi; M. Vakaki; A. Fotinou; V. Petrou; C. Hadjiathanasiou; A. Papathanasiou Background/Aims: Treatment with thyroxine in children with chronic autoimmune thyroiditis (AT) is controversial. The aim of this study is to investigate, by using thyroid ultrasonography...

... loss and rapid rate of weight loss were the most important predictors of low T3 concentrations. Serum free thyroxine concentrations were in the lower normal range. In premenarcheal girls, weight loss was the most important predictor of free thyroxine but this relationship was weaker in postmenarcheal...

... treated with synthetic thyroxine (T 4 ) for 4 weeks, and 44 age-matched euthyroid healthy women. The platelet 5-HT concentration, platelet MAO-B activity, total T 4 and thyroid-stimulating hormone (TSH) levels were determined using spectrofluorimetric methods, radioimmunoassay and fluoroimmunoassay...

... of life. Screening and diagnostic and therapeutic procedures are discussed, as well as outcome and prognosis of the affected infants. Primary thyroid-stimulating hormone screening is almost universally recommended. Early therapy (within 14 days) with appropriate doses of thyroxine (about 10 µg/kg/day...

... receptor Thyroxine Triiodothyronine Bromocriptine Pituitary Hyperthyroidism Original Paper Horm Res 1993:39:229-234 Takehiko Ohzeki3 Keiichi Hanakia Hiroko M otozumi3 Hiroko Ohtaharaa Nobuo Ishitani3 Hirofumi Urashima3 Toshinori Tsukuda3 Kazuo Shirakia Shigekazu Sasakib Hirotoshi Nakamurah Hiroo...

... paper measurement Thyroxine Thyroid-stimulating hormone Congenital hypothyroidism Horm Res 1990;34:219-223 © 1990 S. Karger AG. Basel 0301-0163/90/0346-0219S2.75/0 Blood-Spotted Filter Paper Measurements of Thyroxine and Thyroid-Stimulating Hormone in the Follow-Up of Children with Congenital...

...G. Hennemann; E.P. Krenning In hyperthyroidism, measurement of the serum thyroxine (T 4 ) index or free concentration often suffices to establish the diagnosis. In hyperthyroidism, including 3,3′,5-triiodothyronine (T 3 ) toxicosis, thyrotrophin (TSH) response to thyrotrophin-releasing hormone (TRH...

...-mercaptoimidazole to block fetal thyroid function reduced thyroid hormone concentrations in fetal tissues near term, but this decrease could be partially avoided by infusion of physiological doses of thyroxine to the mothers. Iodine deficiency of the mothers resulted in thyroid hormone deficiency of the developing...

...Shyi-Wu Wang; Hsiao-Fung Pu; Shou-Teh Chiang; Low-Tone Ho; Paulus S. Wang The effects of thyroidectomy and thyroxine (T4) replacement on the release of luteinizing hormone (LH) and gonadotropin-releasing hormone (GnRH) in ovariectomized (Ovx) rats were studied. Immediately after ovariectomy, rats...

...M. Amato; S. Pasquier; A. Carasso; G. Von Muralt Thirty-six preterm infants of less than 34 weeks of gestation with idiopathic respiratory distress syndrome (IRDS) were studied. Eighteen of them were treated with intravenous thyroxine (T 4 ) and compared with 18 control prematures to evaluate...

... of Animal Physiology. Faculty of Sciences. Autonomous University of Barcelona, and bHormone Laboratory, General Hospital Valle Hebron , Barcelona, Spain Key Words. Acute stress Chronic stress Noise Thyrotropin Thyroxine Triiodothyronine Reverse triiodothyronine Abstract. The effects of acute...

...B.M.J. Stringer; D. Wynford-Thomas Lack of species homology in radioimmunoassays can lead to serious errors. We have shown that a highly significant bias results from application of commercially available ‘human’ thyroxine and triiodothyronine assays to rat samples. This paper describes a simple...

...Keith Boler; N.A. Moore Adrenal hypertrophy and steroidogenesis in vitro by dissociated adrenocortical cells from normal intact rats and from rats pretreated for 3–30 days with pharmacologic doses of thyroxine and/or unilateral adrenalectomy were studied. This work addressed the question of whether...

...I. Muranyi-Kovacs; G. Rudali; D. Arnaud The effect of administration of thiourea (5 g/kg in diet) alone or simultaneously with thyroxine (1 mg/l in drinking water) on the frequency of hyperplastic benign osteoma of the skull was studied in AkR mice. Animals treated with both thiourea and thyroxine...

...Surendra K. Varma; John D. Crawford Newborn pups were injected with normal saline (group A) and exogenous thyroxine (group B). Elevated T 4 and decreased TSH levels from day 7 in group B continued until day 35. T 4 and TSH were in normal range by day 42 and were similar to group A. Weight gain...

... to dopamine. Treatment with thyroxine (10 -6 to 10 -5 M) showed a competitive inhibition of thyrotropin release by TRH (0.5 ng), but was without effect on TRH-stimulated PRL release. Cycloheximide (100 µg/ml) blocked a net increase in PRL levels. TRH, nevertheless, significantly increased PRL release...