...Procolo Di Bonito; Domenico Corica; Pierluigi Marzuillo; Anna Di Sessa; Maria Rosaria Licenziati; Maria Felicia Faienza; Valeria Calcaterra; Francesca Franco; Giulio Maltoni; Giuliana Valerio; Malgorzata Wasniewska Background: Reduced central sensitivity to thyroid hormones (THs) has been observed...

... in the lifestyle intervention Obeldicks. Weight status, waist circumference, body fat, insulin resistance, TSH, thyroid hormones (free tri-iodothyronine [fT3] and free thyroxine [fT4]), thyroid volume, and thyroid texture were determined at baseline and in children with available follow-up at the end of the 1-year...

...Giovanni Prezioso; Cosimo Giannini; Francesco Chiarelli This review focuses on the current knowledge of the effects of thyroid hormones on central nervous system differentiation and development in animals and the human fetal brain. The outcomes of children with congenital hypothyroidism...

...Christian Langrock; Johannes Hebebrand; Katharina Radowksi; Eckard Hamelmann; Thomas Lücke; Martin Holtmann; Tanja Legenbauer; Börge Schmidt; Mirjam Frank; Karl-Heinz Jöckel; Thomas Reinehr Background: There is an ongoing discussion whether thyroid hormones are involved in the development...

... were also measured after 6 months of lifestyle intervention in a subset of 43 patients. Results: 109 obese children showed abnormal circulating thyroid hormone concentrations (84 had elevated fT3 levels, 15 elevated TSH, 6 elevated fT4, 3 elevated fT3 and TSH, and 1 elevated fT3, fT4 and TSH levels...

... ± 5.2 μg/l, p < 0.0005). In conclusion, a resetting of the pituitary threshold of the TSH feedback suppression, along with complex alterations in peripheral thyroid hormone levels, may progressively develop in older people, becoming apparent only with extreme senescence. Moreover, the TSH nocturnal...

... when thyrotrophs are chronically exposed to pharmacological TRH-T doses and that TSH pattern is mainly due to the negative feedback of thyroid hormones, even though pituitary TSH reserves may become depleted. Furthermore, prolonged TRH-T administration does not produce hyperthyroidism in euthyroid CVD...

...Roger Abs; Manou Martin; Pierre Blockx A 29-year-old female patient with Graves’ disease who developed thyroid hormone autoantibodies (THAA) under treatment with methimazole is presented. THAA were identified as IgG-ĸ. During a first pregnancy that ended by miscarriage in the 3rd month, the titer...

.... Chorionic gonadotrophin Pregnancy Thyroid Iodide FRTL-5 cells Thyrotrophin Thyroid hormones Horm Res 1990;33:177-183 © 1990 S. Karger AG. Basel 0301-0163/90/0335-0177S2.75/0 Thyroid-Stimulatory Effects of Human Chorionic Gonadotrophin in Early Pregnancy In vivo and in vitro Studies R.L. Kennedy, J...

... between TSH and hCG levels might suggest that hCG also stimulates the gland to increase thyroid hormone output, and the presence of a normal TSH circadian rhythm indicates that the central mechanism of neuroregulation of the pituitary-thyroid axis is preserved in early pregnancy, and (2) in late pregnancy...

... by neuroendocrine signals. In this context, studies performed in hyper- and hypothyroid subjects and in the low triiodothyronine (T 3 ) syndrome, which affects premature infants, have clearly shown that thyroid hormones and in particular T 3 physiologically modulate thymic peptide secretion. In vitro experiments...

...Pavur R. Sundaresan; Shailesh P. Banerjee Thyroid hormone regulation of β-adrenergic receptor-coupled adenylate cyclase activity was studied in rat liver and heart particulate fractions. Thyroidectomy (Tx) increased isoproterenol-stimulated cAMP accumulation in the liver and decreased...

... taken from later time periods but remained depressed. Mean SHBG and thyroid hormones rose and were not significantly different from control values during later periods of the study. Calculated non-SHBG-bound T (NSBT) was below normal in each time period. The close correlation of SHBG values with those...

...Gabriella Morreale de Escobar; Maria Jesus Obregon; Francisco Escobar del Rey It is well known that insufficient production of thyroid hormones during the fetal and neonatal period of development may result in permanent brain damage unless treatment with thyroid hormone is instituted very soon...

... portion. The four specific domains known to be involved in the formation of the thyroid hormones have been assigned to both terminal parts of the polypeptide, a location which could play a role in the process leading to hormone release. The very large ( > 250 kb) Tg gene has been localized on the long...

...Linda V. Oberkotter; Alfred Tenore There is little agreement among published reports of the radioimmunoassayable thyroid hormone content of breast milk, likely due to wide variations in methodology applied. In order to achieve a higher degree of specificity in the determination of T 3 and T 4...

... deiodination of T 4 is preferentially oriented to production of rT 3 only during ketoacidosis. Although changes in thyroid function may reflect the degree of metabolic control of diabetes in a large population, the clinical usefulness of serum thyroid hormone measurements in an individual case still appears...

..., and more pronounced period of activation of the pituitary-thyroid axis and of the peripheral thyroid hormone metabolism was repeatedly observed which lasted until about 36–48 h and was manifested by a highly significant increase of TSH, T 4 , 3,5,3’-triiodothronine (T 3 ) and 3,3’,5’-triiodothyronine (rT 3...

... to be equivalent to catecholamine determinations in helicopter pilots and in motion sickness. They represent the free fraction of thyroid hormones in serum. Timed collections of urine were made in 78 healthy infants and in 43 infants exposed to standardized noise. T 4 and T 3 were determined by RIA on Sephadex...

.... Anencephaly Thyrotropin Prolactin Gonadotropins Growth hormone Thyroid hormones Cortisol Insulin Tests Hormone Res. 15: 159-166 (1981) Endocrine Function in Four Anencephalic Infants1 L. Cavallo, M. Altomare, P. Palmieri, D. Licci, F. Carnimeo. F. Mastro Institute o f Child Health (Head: F...