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Keywords: Targeted drug
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Journal Articles
Hormone Research (1987) 28 (2-4): 196–201.
Published Online: 28 November 2008
... of growth factors (EGF, insulin). At concentrations ≤ 4 µ M , antiestrogens are also cytotoxic and they require accessible estrogen receptors for their action. ‘Estrogen-receptor-targeted drugs’ is therefore a better general term than ‘antiestrogens’ to describe the mechanism of action of these drugs, which...