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Keywords: Tamoxifen
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Journal Articles
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Subject Area:
Endocrinology
Hormone Research (1989) 32 (Suppl. 1): 261–265.
Published Online: 02 December 2008
...V. Craig Jordan Animal models all demonstrate that tamoxifen is tumouristatic in the case of breast tumours and long-term or indefinite therapy is required to prevent the appearance of tumours. When treatment is stopped, tumours appear spontaneously or can be encouraged to re-appear with oestrogen...
Journal Articles
Hormone Research (1989) 32 (Suppl. 1): 181–182.
Published Online: 02 December 2008
...H.J. Stewart The question of which breast cancer patients to treat has been addressed by reviewing posters presented at the International Symposium on Endocrine Therapy. To date, tamoxifen therapy is the dominant type of adjuvant treatment in postmenopausal patients. The most promising results have...
Journal Articles
Hormone Research (1989) 32 (Suppl. 1): 189–197.
Published Online: 02 December 2008
... to evaluate their optimal sequence. Tamoxifen has become the most commonly used endocrine therapy for advanced breast cancer due to its few side effects and an overall response rate of 35%. Crossover data from randomised trials, comparing tamoxifen with either ablative, additive or inhibitive treatment...
Journal Articles
Hormone Research (1987) 25 (4): 199–205.
Published Online: 28 November 2008
...), estradiol and testosterone (total and free fraction) in 9 sexually mature men and 7 women under basal conditions and after treatment with the antiestrogen tamoxifen (2 × 10 mg/day p.o.) for 7 days. In women, the medication was started on day 7 ± 1 of their menstrual cycles. To calculate the MCR, synthetic...
Journal Articles
Hormone Research (1987) 28 (2-4): 219–229.
Published Online: 28 November 2008
... present our own experience of the use of antiestrogens in this field. We have compared the results of clomiphene citrate (CC) to those of tamoxifen (TAM) in a randomized study including 66 infertile women presenting eugonadal anovulation (n = 26) or LPD (n = 40). Both drugs obtained the same pregnancy...
Journal Articles
Hormone Research (1985) 22 (3): 172–178.
Published Online: 28 November 2008
...S.W.J. Lamberts Estrogens prevent or diminish the sensitivity to dopamine of prolactin (PRL) secretion by cultured rat pituitary cells. Cultured tumor cells prepared from a transplantable rat PRL-secreting tumor were insensitive to dopamine and bromocriptine, while the antiestrogen tamoxifen...
Journal Articles
Journal Articles
Hormone Research (2000) 54 (5-6): 296–300.
Published Online: 28 September 2001
..., at a chosen time and/or in a given cell type will further improve such studies, and will facilitate the generation of animal models for human diseases. To create targeted somatic mutations in the epidermis, we established transgenic mice expressing the bacteriophage P1 Cre recombinase or the tamoxifen...
Journal Articles
Journal Articles
Hormone Research (2000) 53 (1): 36–39.
Published Online: 11 August 2000
...Yasuo Hozumi; Mikihiko Kawano; Yoji Hakamata; Michio Miyata; V. Craig Jordan Tamoxifen, a nonsteroidal antiestrogenic antitumor agent, has weak estrogen-like effects on lipid metabolism, however, the mechanism remains unknown. We previously reported that tamoxifen decreases the activity...