... in adulthood. However, the mechanism underlying this early programming remained unclear. Estrogen-related receptor gamma (ERRγ) is an orphan nuclear receptor with a high expression in the human placenta, particularly ERRγ1. ERRγ has been proposed to play a central role in controlling genes involved in energy...

...: After uncomplicated pregnancies, placentas (n = 48) were collected at term delivery of singleton infants who were appropriate for gestational age (AGA) or small for gestational age (SGA) (n = 24 in each subgroup). Placental mtDNA content was assessed by real-time PCR, placental SOD activity...

..., instructions or products referred to in the content or advertisements. Insulin-like growth factor-I Estrogen receptor Progesterone receptor Placenta Small for gestational age Fetal growth restriction is a complex problem of pregnancy, arising from multiple etiologies, including environmental...

... appropriate for gestational age (AGA), small for gestational age (SGA) and large for gestational age (LGA) newborns, we studied the placentas from 35 AGA, 30 SGA and 28 LGA pregnancies. The IGF-I, IGF-II and IGF-I receptor (IGF-IR) placental mRNA and protein contents were determined in the basal and chorionic...

... available for intrauterine growth to the fe- tal tissues and relay back to the placenta the degree of mismatch between the actual fetal nutrient supply and the fetal nutrient demands for growth. They affect intrauterine growth by anabolic and catabolic actions on fetal metabolism and by altering...

... to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Intrauterine growth retardation Fetal growth Catch-up growth Undernutrition Placenta Programming Horm one R e se a rch Peter D. Gluckman Jane E. Harding Research...

... or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Growth hormone Insulin-like growth factors Development Fetus Placenta mRNA Transgenic animals Horm one R e se a rch Session 3 GH and Gonadal Hormones Horm Res 1996;45:61-66...

...C.L. Coulter; V.K.M. Han The patterns of expression insulin-like growth factor-II (IGF-II) and IGF-binding protein-1 (IGFBP-1) mRNAs were compared between term human and rhesus monkey placenta using in situ hybridization histochemistry. Since IGFs and IGFBPs are paracrine factors...

... responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Insulin-like growth factor Insulin-like growth factor-binding protein Gene targeting Functional compensation Spleen Uterus Placenta Hormone...

... and rat brain, and in human liver and placenta. In brain, the central distribution of CRFBP shares some regional overlap with CRF receptor-binding sites. Additionally, in hypothalamic and limbic structures, CRFBP has been identified in association with CRF-expressing cell groups. CRFBP has been also...

... correlated, pointing to a key role of the placenta in the regulation of fetal growth. It is therefore important to understand the molecular mechanisms involved in regulating placental development and endocrine functions. TGFα and EGF might play major roles as suggested by the modulation of their receptors...

...William W. Hay, Jr. The exchange of nutrients between placenta and fetus involves three major mechanisms: (1) direct placental transfer of nutrients from the maternal to the fetal plasma; (2) placental metabolism and consumption of nutrients; (3) placental metabolism of nutrient substrates...

... these findings, definitive evidence is still lacking that PL contributes to fetal growth and development in utero. Fetus Embryo Pituitary growth hormone Variant growth hormone Placenta Growth Implantation Placental lactogen 3 12 2008 © 1992 S. Karger AG, Basel 1992 Copyright / Drug...

...D. Evain-Brion; E. Alsat; V. Mirlesse; M. Dodeur; M.L. Scippo; G. Hennen; F. Frankenne In this study, we have cultured in vitro purified trophoblastic cells from first-trimester and term human placenta. These cells were obtained by specific enzymatic digestion and centrifugation through a Percoll...

...V. Mirlesse; E. Alsat; C. Fondacci; D. Evain-Brion Epidermal growth factor (EGF) receptors were studied during the in vitro differentiation of human trophoblast cells from first- and third-trimester placentas. Cytotrophoblasts were isolated by enzymatic digestion and purified on a discontinuous...

..., instructions or products referred to in the content or advertisements. Insulin-like growth Factor-I Epidermal growth factors Receptors Placenta Trophoblastic cells Horm Res 1991;35:246-251 @ 1991 S. Karger AG. Basel 0301-0163/91 /0356-0246S2.75/0 Epidermal Growth Factor Enhancement of Insulin-Like...

.... It is unclear whether the large free α-subunit is only a secretory product or whether it is also present in tissue. Herein were studied the molecular size, the isoelectric pH, and the recombining activity of free α-subunit obtained from pituitary and placenta extracts. Sephadex exclusion chromatography showed...

...W.E. Stumpf; M. Sar; R. Narbaitz; S. Huang; H.F. DeLuca After injection of 3 H-1,25-(OH)-vitamin D 3 into rats on days 18 and 20 of pregnancy, autoradiograms of placenta and fetal membranes show nuclear concentration of radioactivity in certain cells. This nuclear concentration is abolished when...

... Metabolic Pathways and Tissue D istribution1 Dina N o ff and Samuel Edelstein Biochemistry Department, The Weizmann Institute of Science, Rehovot Key- Words. Vitamin D Pregnancy Placenta Lactation Milk Abstract. Replacing body stores of vitamin D in pregnant rats with radiolabelled cholecalciferol...

..., quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Placenta Proliferation Differentiation Migration Apoptosis Insulin-like...