... physical and psychological burden. Little is known about the effects of pituitary and ovarian iron contents on ovarian reserve and function. Hence, this study aimed to assess ovarian reserve and pituitary-gonadal axis function in adolescent females with TDT and correlate them with pituitary and ovarian...

... confirmed based on histologic evaluation of a resected pituitary tumor or remission after transsphenoidal surgery. Results: We recorded a rare incidence of false-negative IPSS results in 5 out of the 142 IPSS procedures (3.5%), performed in 4 unique patients. Patients with negative IPSS did not differ...

...Altino Sá Meira; Arthur Lyra; Cristiane Kochi; Daniel de Faria Guimarães; Arthur Castello Berchielli Nunes; Guilherme Vieira Peixoto; Stella Gallucci Zamot; Tatiane Sousa e Silva; Antônio José da Rocha; Carlos Alberto Longui Introduction: Ectopic posterior pituitary (EPP) is a malformation...

... children consecutively diagnosed with GHD before the age of 4 years. The prevalence of hypothalamic-pituitary (HP) alterations at MRI and the associations with age and either isolated GHD (IGHD) or multiple pituitary hormone deficiency (MPHD) were assessed. Results: The prevalences of IGHD and MPHD were...

...Mariana R. Haedo; Juan Gerez; Mariana Fuertes; Damiana Giacomini; Marcelo Páez-Pereda; Marta Labeur; Ulrich Renner; Gunter K. Stalla; Eduardo Arzt Research performed on the pituitary has proven that cytokines play an important role in maintaining pituitary physiology, affecting not only cell...

...Adrian F. Daly; Maria A. Tichomirowa; Albert Beckers Pituitary adenomas occur in a familial setting in about 5% of all cases, and over half of these are due to multiple endocrine neoplasia type 1 (MEN1) and Carney’s complex (CNC). Non-MEN1/CNC familial pituitary tumours of all tumour phenotypes...

.../polydipsia due to an adrenocorticotropic hormone-secreting pituitary adenoma. The dog underwent curative transsphenoidal hypophysectomy and has remained in complete remission in the 3.5 years since surgery. These findings have implications for the use of canine corticotroph adenomas as a direct model...

...Adrian F. Daly; Maria A. Tichomirow; Albert Beckers Background: Pituitary adenomas occur in a familial setting in about 5% of all cases and over half of these are due to multiple endocrine neoplasia type 1 (MEN1) and Carney complex (CNC). Since the late 1990s, we have described non-MEN1/CNC...

...I. Pellegrini-Bouiller; I. Morange-Ramos; A. Barlier; G. Gunz; A. Enjalbert; P. Jaquet The anterior pituitary-specific transcription factor Pit-1 (also known as GHF-1) was initially identified and cloned as a transactivator of the GH and PRL genes, and later as a regulator of the TSHβ gene...

... by a decreased number of Leydig (and Sertoli) cells and on the other hand in the hypothalamo-pituitary complex characterized by a decreased luteinzing hormone (LH) pulse amplitude, LH pulse frequency being maintained. As the responsiveness of the gonadotrophs to gonadotropin-releasing hormone (GnRH) remains...

... hypothalamic-pituitary-adrenal function. Excess androgen production by the adrenals is thus decreased. Despite standard glucocorticoid replacement doses (12.5-40 mg, 10.5-27 mg/m 2 /day hydrocortisone equivalents) 4 of 7 patients ranging in age from 14 to 33 years had abnormalities of the pituitary on MRI...

...S. Cianfarani; R.M. Nicholl; S. Medbach; M.C. Charlesworth; M.O. Savage We describe 5 children, 4 girls, aged 4-14 years with evolving hypothalamic-pituitary dysfunction. They had presenting features, isolated or combined, of polyuria and polydipsia (n = 3), weight gain and hyperphagia (n = 3...

... with the selective pituitary type of thyroid hormone resistance for more than 7 years to clarify whether bromocriptine was an effective treatment or not. Levels of T3 (before: 2.44 ± 0.64 nmol/l, mean ± SD) and TSH (4.81 ± 2.52 mU/1) were significantly decreased during therapy (T 3 : 2.15 ± 0.44 nmol/l; TSH: 1.59...

.... The literature has suggested that the effects of bromocriptine on storage and synthesis may be responsible for its effects on tumor size. It was felt that TRH stimulation would more accurately reflect storage and synthesis, and thus correlate better with tumor size. The pituitary was initially debulked via...

...V. May; R.E. Mains; B.A. Eipper The ability of various cofactors to substitute for ascorbate in the biosynthesis of α-aidated peptides from pro-ACTH/endorphin (PAE) was compared in corticotrope tumor cells (AtT-20) and in primary anterior and intermediate pituitary cultures. In all three systems...

..., instructions or products referred to in the content or advertisements. Growth hormone Lipolysis Free fatty acids Lipoproteins LDL-cholesterol Acromegaly Pituitary Ketone bodies Ketone body kinetics Insulin Triglycerides Insulin-like growth factor-1 Horm Res I991:36(suppl I):36 40 Growth...

.... It is unclear whether the large free α-subunit is only a secretory product or whether it is also present in tissue. Herein were studied the molecular size, the isoelectric pH, and the recombining activity of free α-subunit obtained from pituitary and placenta extracts. Sephadex exclusion chromatography showed...

... sharply between 02.00 and 06.00 h, showing the highest concentration at 06.00 h. In contrast, no significant changes in α-MSH content were detected in the lateral hypothalamus during a 24-hour period. Pituitary α-MSH also showed a diurnal variation which was different from that in the two hypothalamic...

...Maija-Liisa Laakso; Tarja Porkka-Heiskanen; Gunnar Johansson; Mikael Peder; Elina Nikanne In order to find out whether different light spectra have any role in regulating the gonadotropin levels in male rats, we compared the 24-hour patterns of plasma and pituitary gonadotropins in rats kept for 7...

... to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. TSH Acute cold Morphine Naloxone Pituitary Thermoregulation Hormone Res. 27: 95-101 (1987) © 1987 S. Karger XG. Basel 0 3 0 1 - 0 163/87/0272-0095S2.75/0 Dual Dose...