...J.J. Legros; V. Geenen When they were discovered by Acher and co-workers, neurophysins were thought to act as carriers for the active nonapeptides vasopressin (AVP) and oxytocin (OT) and were then recognized as the inactive fragment of a precursor with a higher molecular weight (propressophysin...

... in both sexes.The cells of the supraoptic nucleus and PVN produce AVP or oxytocin and coexpress tyrosine hydroxylase. These nuclei are examples of neuron populations that seem to stay perfectly intact in ageing. Parvicellular corticotropin-releasing-hormone (CRH)-containing neurons are found throughout...

...Janet A. Amico; Janine E. Janosky; Sue M. Challinor; Judy L. Cameron A diurnal pattern in oxytocin concentrations is present in cerebrospinal fluid (CSF) removed from the spinal subarachnoid space of monkeys, with elevated levels occurring in the early light hours. In order to investigate...

... peptides, namely vasopressin and oxytocin, are themselves capable of modifying behaviour. In this paper the author discusses current understanding of the anatomy and physiology of the main central vasopressinergic and oxytocinergic pathways, followed by a description of the principal actions of exogenously...

...Sue M. Challinor; Judy L. Cameron; Janet A. Amico Cerebrospinal fluid (CSF) samples were collected at frequent intervals (every 10-15 min) to determine if oxytocin pulses were present in the CSF of monkeys. Temporary indwelling subarachnoid catheters, with the tip of the catheter at the T12-L1...

...Giuseppe Paolisso; Saverio Sgambato; Nicola Passariello; Roberto Torella; Dario Giugliano; Sabato Mignano; Michele Varricchio; Felice D’Onofrio Phramcological doses of oxytocin administered in basal conditions evoked a rapid surge in plasma glucose and glucagon levels followed by a later increase...

...Paolo Chiodera; Vittorio Coiro The present study was performed in order to establish whether angiotensin II (ANG II) and/or insulin-induced hypoglycemia exert their oxytocin (OT)-releasing effects by interacting with a GABAergic pathway. For this purpose, in 14 normal men the OT responses to ANG II...

...Giuseppe Paolisso; Saverio Sgambato; Dario Giugliano; Gennaro Pizza; Paola Tesauw; Michele Varricchio; Felice D’Onofrio In insulin-dependent (type 1) diabetic subjects (n = 7) with intact hormone response to hypoglycaemia, oxytocin infusion (0.2 mU/min over 60 min) produced significant rises...

...J.J. Legros; V. Geenen; T. Carveli; H. Martens; M. Andre; J.L. Corhay; M. Radermecker; P.F. Zangerle; G. Sassolas; C. Gharib; M. Vantyghem; J. Lefebvre Vasopressin-neurophysin (hN p I), oxytocin-neurophysin (hN p II) and blood osmolality were assayed before any treatment in basal conditions in 35...

...P. Chiodera; C. Salvarani; A. Bacchi-Modena; R. Spallanzani; C. Cigarini; A. Alboni; E. Gardini; V. Coiro Oxytocin (OT) administration has been shown to inhibit adrenocorticotropic hormone (ACTH)/cortisol secretion in several experimental conditions. In the present study, the plasma OT responses...

.... Neurophysins Depression Mania Vasopressin Oxytocin Neurobiology Clinic Horm Res 1989;31:55-58 © 1989 S. Karger AG, Basel 0301-0163/89/0312-0055S2.75/0 Increased Basal Plasma Vasopressin-Neurophysin in Mania J.J. Legrosa, M. Ansseaub aNeuroendocrinology Section and bBiological Psychiatry Unit, CHU...

...Charles R. Wesley; Joseph P. Gilmore We determined the effect of oxytocin, α-melanocyte stimulating hormone (α-MSH) and arginine vasotocin on renal function of the macaque monkey. The only significant effect of the peptides was that α-MSH had an antidiuretic effect and vasotocin had both...

...P. Chiodera; V. Coiro; L. Camellini; G. Rossi; D. Pignatti; R. Volpi; E. Roti Inthis study we have examined the effect of the administration of oxytocin on basal blood concentrations of insulin, glucagon, cortisol, growth hormone, and on the dynamic secretory response of these hormones...

... or AVT. Oxytocin had no effect on plasma prolactin values. The intravenous administration of 1 µg of (deamino-1,6 dicarba, 8-arginine)-vasotocin caused a significant elevation of plasma prolactin 10 and 20 min after injection. However, the injection of another analogue of AVT, (4-leucine, 8-arginine...

..., sexual excitement in males and milking caused the largest increases in plasma concentration. Oxytocin injections and mild stress caused significant but smaller increases in plasma prolactin sometimes seen as a rise in jugular vein concentrations only. Plasma prolactin fell on fasting and after insulin...

... AMP Gluconeogenesis Oestradiol Oxytocin Hormones I: 233-256 (1970) Review Mechanism of Hormonal Action Ronald S. Snart Department of Zoology, The University, Sheffield Abstract. A review of evidence supporting a general mechanism of action of steroid hormones has been made by comparing...

... with 0.01 M sodium thioglycollate at 65°C for 5 min. The oxytocic activity was antagonized neither by 1.4 × 10 -6 M atropine nor 3.3 × 10 -7 M phenoxybenzamine. 21 11 2008 Ox neurohypophysis Neurophysin Exclusion chromatography Oxytocin Vasopressin Milk ejection Antidiuresis Hormone...

.... The perfusion of 60 µ C i 3 H-epinephrine to ratspregnant for 21 days resulted in a significant accumulation of the tracer in the fetal heart. This accumulation was markedly declined by pre-administration of progesterone, estrogens, and oxytocin in the pregnant rats and by maternal adrenalectomy...

...Theodor H. Lippert; Alfred O. Mueck; Harald Seeger; Andreas Pfaff For a long time, oxytocin was regarded as a pregnancy hormone released by the hypophysis to stimulate labour and milk ejection. In the present survey, data have been collected from the literature to show the spectrum of the hitherto...

...José L. Chicharro; Jesús Hoyos; Fernando Bandrés; Felix Gómez Gallego; Margarita Pérez; Alejandro Lucía Aims: This study was designed to explore the plasma oxytocin (OT) response to exercise until exhaustion in trained male cyclists. Methods: Twelve professional cyclists (EXP group; age: 26 ± 2...