..., instructions or products referred to in the content or advertisements. Type 1 diabetes mellitus Bone mineral density Microarchitecture Osteoporosis Bone turnover marker The global prevalence and incidence of type 1 diabetes mellitus (T1DM) in children and adults is increasing [1]. More than 1...

... to in the content or advertisements. Bone mineral density Fracture Inflammatory bowel disease Duchenne muscular dystrophy Inflammation Glucocorticoid Osteoporosis Acute lymphoblastic leukaemia Skeletal fragility in childhood due to chronic disease is a systemic disorder of abnormal bone growth...

..., particularly in those with moderate-to-severe disease. Orthopaedic intervention in combination with bisphosphonate therapy has resulted in significant improvements in patient mobility [ 4 ]. Osteogenesis imperfecta Osteoporosis Bisphosphonates Bisphosphonate therapy did not result...

...Giampiero I. Baroncelli; Silvano Bertelloni Bisphosphonates are widely used for the prevention and treatment of osteoporosis in adulthood. In the last years, bisphosphonates have been increasingly used in pediatric patients for the treatment of a growing number of disorders associated...

... geometry Congenital adrenal hyperplasia Androgens Periosteal bone apposition Glucocorticoids Osteoporosis Congenital adrenal hyperplasia (CAH) is a group of autosomal recessive disorders resulting from deficiency of one of the five enzymes required for cortisol synthesis in the adrenal cortex...

...Hooi Leng Ooi; Julie Briody; Andrew Biggin; Chris T. Cowell; Craig F. Munns Aim: To evaluate the safety and efficacy of 12 months of zoledronic acid (ZA) administered every 6 months to children with osteoporosis. Methods: Retrospective cohort study of 27 patients (16 male, 11 female) treated...

...B. Tüysüz; A. Bursalı; Z. Alp; N. Suyugül; C.M. Laine; O. Mäkitie Background/Aims: Osteoporosis-pseudoglioma (OPPG) syndrome is a rare disorder characterized by congenital or infancy-onset visual loss and severe juvenile osteoporosis. OPPG is caused by homozygous mutations in the low-density...

...Ian R. Reid Background: A number of disease states and drugs can upset the balance between bone formation and resorption resulting in increased fracture risk. Glucocorticoids are the most recognized cause of secondary osteoporosis. Hypogonadism, weight loss, and chronic inflammation are other...

... to in the content or advertisements. Congenital adrenal hyperplasia 21-Hydroxylase deficiency Obesity Hypertension Osteoporosis Fertility Congenital adrenal hyperplasia (CAH) due to 21-hydroxylase deficiency (21OHD) is one of the most common inborn conditions following an autosomal recessive...

... 2002;17:695–702. Inflammation Bone Growth Osteoporosis Interleukin-6 During childhood, diseases with chronic or recurrent inflammation, such as juvenile idiopathic arthritis (JIA), inflammatory bowel diseases and cystic fibrosis, have a detrimental effect on skeletal development...

...E.F. Eriksen; B.L. Langdahl Consensus and WHO definitions of osteoporosis are provided. The pathogenesis of the disorder has genetic, hormonal and environmental influences which affect peak bone mass, perimenopausal bone loss and age-dependent bone loss. Peak bone mass is mainly genetically...

... Antiestrogen Osteoporosis Abstract Selective estrogen receptor modulators (SERMs) comprise a group of structur­ ally diverse compounds which are distinguished from estrogens by their ability to interact with the estrogen receptor but to act as either an estrogen agonist or antagonist depending on the target...

...E. Schönau; E. Werhahn; U. Schiedermaier; E. Mokow; H. Schiessl; K. Scheidhauer; D. Michalk In connection with the prevention of osteoporosis, paediatrics is challenged with ensuring the optimal formation of the skeletal system with maximal bone strength during childhood and youth. Biomechanical...

... responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Bone formation IGF binding proteins Insulin-like growth factors Osteoblasts Osteoporosis Symposium III: Bone Biology and Growth Horm Res...

... new bone formation occurs. Abnormalities of GH secretion have also been implicated in the development of osteoporosis, but the effect of GH treatment on bone mass in such patients is disappointing. Sex steroids have an important role to play in the acquisition of bone mass, and reduced sex steroid...

... for Osteoporosis KAGInenrsoyauwbWliontohl-irlshdimkosermgroonweth factor Osteoporosis AGrobrlosetwirnathcsktheolertmalognreow(GthHa)nadnbdoinnesurelimn-olidkeelinggro. wInthviftarcot,obrsot(hIGagFesn) tpsldaiyspalacyenatnraal­ bRoelcicenptrionpveirvtioess,tuadnidesphaatvieendtsemwoitnhstarcartoemd...

...P.D. Delmas Several recent studies show that bone loss continues in the elderly, and that various regimens are still effective in the elderly to stop bone loss. Thus, diagnostic procedures for osteoporosis should be considered in elderly women, i.e. measurement of bone mass by dual energy X-ray...

...Jean-Yves L. Reginster Several approaches may be suggested for prevention or treatment of senile osteoporosis. In elderly patients, an association of calcium and vitamin D supplementation has been shown to reduce nonvertebral fractures up to 40% over an 18-month period. Calcitonin, given...

... support the hypothesis that endogenous CT physiologically has a bone protective role. They furthermore are consistent with the view that endogenous CT itself is not pathogenetically involved in the development of osteoporosis. 17 12 1991 28 04 1992 3 12 2008 © 1992 S. Karger AG...

... osteoporosis. On the contrary, changes in circulating CT levels appear to be secondary to the changes in bone turnover, whether in postmenopausal osteoporosis, after estrogen replacement therapy or in renal stone formers. We found a marked CT deficiency after thyroidectomy, radioactive iodine treatment...