...Robert C. Olney Background: Long-term treatment with high-dose glucocorticoids (GCs) has profound effects on bone metabolism and linear growth. Bone metabolism is a balance between bone resorption by osteoclasts and new bone formation by osteoblasts. Systemically, GC treatment reduces circulating...

...K. Chihara; T. Sugimoto Bone remodelling is a cyclical phenomenon consisting of osteoclastic bone resoφtion followed by osteoblastic bone formation. Although recent evidence suggests that GH participates in bone remodelling, the exact mechanism remains unclear. The present series of in vitro...

... responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Bone formation IGF binding proteins Insulin-like growth factors Osteoblasts Osteoporosis Symposium III: Bone Biology and Growth Horm Res...

..., instructions or products referred to in the content or advertisements. Osteoblasts Bone Biomechanics Modelling Remodelling Pharmacology Endocrinology These mechanisms interact with bone in a way that no single kind of cell can. Modelling, rather than osteoblasts alone, provides nature’s...