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Keywords: Nescient helix-loop-helix 2
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Journal Articles
A Two-Base Deletion –439delGC in the Melanocortin-4 Receptor Promoter Associated with Early-Onset Obesity
Available to PurchaseKaisa Valli-Jaakola, Jorma J. Palvimo, Marita Lipsanen-Nyman, Veikko Salomaa, Leena Peltonen, Kimmo Kontula, Camilla Schalin-Jäntti
Journal:
Hormone Research in Paediatrics
Hormone Research (2006) 66 (2): 61–69.
Published Online: 26 July 2006
..., but have so far not been reported. Transcription factor nescient helix-loop-helix 2 (Nhlh2) is a novel obesity candidate gene. We searched for mutations in MC4R promoter and Nhlh2 gene in 152 children with severe early-onset obesity. Lean subjects (n = 447) served as controls. Methods: MC4R promoter...