... , dominates the clinical expression. Size. Pituitary tumours in MEN1 are larger than common variety pituitary tumours, with macroadenoma in 85% of the MEN1 cases compared with 42% of the common variety cases [ 3 ]. Angiogenesis MEN1 Mouse p27 Kip1 Pituitary tumour Prolactinoma Tumour...

..., instructions or products referred to in the content or advertisements. Aging Epdermal growth factor Fertility Mouse Ovary Uterus Horm Res 1993;39(suppl 1):32 36 O. Tsutsumia Y. Taketania T. Okab Depariment of Obstetrics and Gynecology. Faculty o f Medicine. University of Tokyo, Hongo, Bunkyo-ku...

...Stefan Lindskog; Bo Ahrén The effects of the two intrapancreatic peptides galanin and pancreastatin on basal and stimulated insulin and glucagon secretion in the mouse were compared. It was found that at 2 min after intravenous injection of galanin or pancreastatin (4.0 nmol/kg), basal plasma...

...I.F. Lau; S.K. Saksena; M.C. Chang The concentrations of testosterone (T), 5α-dihydrotestosterone (5α-DHT) and Δ 4 -androstenedione (Δ 4 A) in the circulating blood were increased by a single subcutaneous injection of 10 IU of hCG in the mouse. The response of androgen synthesis to hCG stimulation...

...R.K. Rastogi; P.K. Saxena; L. Iela The mouse epididymis was studied to localize histochemically a number of hydroxysteroid dehydrogenases in the various zones. The epithelium of the posterior half of the initial segment (head) and the anterior half of the middle segment (body) shows a strong...

...Clifford J. Rosen Background: Mouse models that include spontaneous mutations, as well as those carrying allelic differences, have been extremely useful in clarifying the role of skeletal and circulating insulin-like growth factor I (IGF-I) in peak bone acquisition. The role of peroxisome...

...Arup Kumar Indra; Mei Li; Jacques Brocard; Xavier Warot; Jean-Marc Bornert; Christelle Gérard; Nadia Messaddeq; Pierre Chambon; Daniel Metzger Gene targeting in the mouse is a powerful tool to study mammalian gene function. The possibility to efficiently introduce somatic mutations in a given gene...