... describing an association between patients with DLK1 deficiency and an impaired metabolic profile. The patient was treated for 2 years with GnRH agonists with ongoing biochemical follow-up into adolescence. Conclusion: This case illustrates the susceptibility to metabolic derangement for patients...

...Anders Tidblad; Jan Gustafsson; Claude Marcus; Martin Ritzén; Klas Ekström Introduction: Growth hormone (GH) is a central hormone for regulating linear growth during childhood and also highly involved in the metabolism of lipids, carbohydrates, and protein. However, few studies report on how...

...Leena Antikainen; Jarmo Jääskeläinen; Henrikki Nordman; Raimo Voutilainen; Hanna Huopio Background: Maternal gestational diabetes mellitus (GDM) and overweight are associated with an increased risk of obesity and the metabolic syndrome in the adult offspring. We studied the influence of maternal...

...-onset obesity on the cross talk between metabolic state, testes, and skeleton at late puberty. Methods: A cohort of adolescent and young adult males with severe childhood-onset obesity ( n = 21, mean age 18.5 years) and an age-matched control group were assessed for testicular hormones and X-ray...

... in younger individuals. We investigated the relationship between PEDF and various metabolic biomarkers in young healthy volunteers (HV) and similar-aged patients with diabetes (type 1 and type 2). Methods: A fasting blood sample was collected in 48 HV, 11 patients with type 1 diabetes (T1D), and 11 patients...

...Daniela A. Rubin; Susan J. Clark; Andrea M. Haqq; Diobel M. Castner; Jason Ng; Daniel A. Judelson Background: Prader-Willi syndrome (PWS) is characterized by excessive adiposity. Excess adiposity negatively affects hormonal and metabolic responses to aerobic exercise. This study determined whether...

... exhibit decreased body weight, food intake, free fatty acid levels and fat pad mass weight and moderately decreased linear growth. In humans, intravenous infusion of UAG in normal subjects enhances the early insulin response to meals, improves glucose metabolism and insulin sensitivity and inhibits...

... to surgical patients, nitrogen retention is regulary seen, and in most situations fast mobilization takes place. The present data indicate that GH has a beneficial effect on the healing processes after surgery and trauma. Growth hormone Indications Metabolism Surgery 5 12 2008 © 1993 S...

... recent studies of the metabolic effects of recombinant human IGF-I in normal humans. These studies demonstrated that under euglycemic conditions, IGF-I had potent effects on glucose (hepatic and peripheral), lipid and amino acid metabolism that closely resemble those of insulin, despite a concomitant...

...M.J. Caballero In androgen target tissues, testosterone undergoes extensive biotransformation to 5α-dihydrotestosterone which in turn is metabolized into 5α-androstane-3α, 17β-diol and 5α-androstane-3β, 17β-diol. From studies mainly in the prostate, it has been shown that 5α-androstane-3β, 17β-diol...

... hormone releasing hormone, and (4) the obese state is characterized by a defect in GH release which can be reversed by weight loss. Growth hormone Fat distribution Metabolism © 1992 S. Karger AG, Basel 1992 Copyright / Drug Dosage / Disclaimer Copyright: All rights reserved. No part...

...Michael B. Ranke GH effects certain changes in the metabolism of lipids and body water in humans. The effects of GH, such as high blood pressure, an increase in cholesterol and triglycerides, and lipoatrophy, among others, must, however, be seen in the context of the diverse disorders being treated...

... or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Aging Insulin Glucose Metabolism Horm Res 1992:38:46-50 Charles CoueC Jacques...

...-like growth factor I Pharmacology Metabolism Horm Res 1990;33(suppl 4):77-82 ©1990 S. Karger AG, Basel 0301-0163/90/3310-0077$2.75/0 Pharmacological Aspects of Growth Hormone Replacement Therapy: Route, Frequency and Timing of Administration Jens O.L. Jorgensen, Jens Möller, Niels Möller, Torsten...

... to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Androgen Metabolism Genital skin HPLC 17β-Hydroxysteroid dehydrogenase 5α-Reductase Development 22 03 1989 2 08 1989 2 12 2008 Horm Res 1989;32...

...(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Growth hormone Metabolism Protein Amino acids Lean body mass Insulin IGF-I Horm Res I99l;36(suppl 1):41 43 © 1991...

.... There is a positive association between fat mass and fasting serum insulin in hypopituitarism, suggesting insulin resistance. Hypoglycaemia unresponsiveness, rather than insulin sensitivity, is the feature of growth hormone deficiency. Basal metabolic rate (expressed per kg body weight) is increased in acromegaly...

.... Interleukin-1 Glucose Insulin Diabetes Glucose tolerance Glucocorticoids Metabolism Horm Res 1989;31:94-99 © 1989 S. Karger AG, Basel 0301-0163/89/0312-0094S2.75/0 Interleukin-1 and Glucose Homeostasis: An Example of the Biological Relevance of Immune-Neuroendocrine Interactions Hugo O. Besedovsky...

... Direct radioimmunoassay Metabolism 16 09 1986 12 01 1987 28 11 2008 Original Papers Hormone Res. 27: 61-68 (1987) © 1987 S. Karger AG, Basel 0301-0163/87/0272-0061$2.75/0 Serum and Urinary Estrone Sulfate during the Menstrual Cycle, Measured by a Direct Radioimmunoassay, and Fate...

... 10.2 to 3.7 and 2.1 to 0.3, respectively (p < 0.01). These results indicate that intestinal bacteria participate in the metabolism of aldosterone during enterohepatic circulation in man. 24 03 1987 19 10 1987 28 11 2008 Sodium homeostasis Renin Bacterial conversion...