... on body mass index (BMI) in patients with CPP remain controversial. Objective: This systematic review and meta-analysis aimed to evaluate the association between GnRHa treatment and BMI in patients with CPP. Methods: A systematic search of databases, PubMed, EMBASE, and Web of Science published before...

..., instructions or products referred to in the content or advertisements. 2023 Growth hormone therapy Puberty Children Idiopathic short stature Meta-analysis Growth hormone (GH) promotes statural growth and plays an integral role in metabolism 1 . It improves linear growth via hepatic...

...Adélaïde Durand; Maithé Tauber; Bharat Patel; Pascale Dutailly Background/Aims: A meta-analysis was undertaken to assess the effect of triptorelin 11.25 mg 3-month prolonged-release formulation in central precocious puberty (CPP). Methods: All available clinical studies with triptorelin 11.25 mg...

...Mario Miccoli; Silvano Bertelloni; Francesco Massart Background/Aims: Although recombinant human growth hormone (rhGH) is not approved to treat short stature of achondroplasia (ACH), some studies suggested growth improvement during short-term rhGH treatment. Methods: A meta-analysis of rhGH therapy...

... with hMG in IVF by conducting a systematic overview and meta-analysis of the evidence in the literature from randomized trials comparing the two gonadotropins. The data were extracted and pooled from eight studies that satisfied the inclusion criteria. The results show that FSH performs significantly...

.... Randomized controlled trial Non-randomized trial Observational study Systematic review Meta-analysis Clinical decision making Many difficult decisions – in medicine and much more widely – must be made where the necessary or desired information is unavailable or inadequate, leading to what...