... towards the development of hepatic fibrosis via AT 1a receptor. 3 H-proline incorporation studies were done to investigate the effects of Ang II and losartan on HSCs collagen synthesis. HSCs were plated in 96-well culture dishes and allowed to grow to inconfluency in DMEM containing 10% FBS. After...

... tissues raised the question of whether or not aldosterone escape occurs in these tissues. Method: Spontaneously hypertensive rats were treated with enalapril (20 mg/kg/day) and losartan (50 mg/kg/day) for 20 weeks; untreated spontaneously hypertensive and Wistar rats were used as positive and normal...