... insulin requirements were ≥1 IU/kg body weight/day, compared to patients with in-sulin requirements <1 IU/kg body weight/day (0.270 ± 0.027 g/L, n = 10 vs. 0.241 ± 0.036 g/L, n = 15; p = 0.048; Fig.  1 ). Adolescence Childhood diabetes Type 1 diabetes Insulin sensitivity Liver...

...Pavur R. Sundaresan; Shailesh P. Banerjee Thyroid hormone regulation of β-adrenergic receptor-coupled adenylate cyclase activity was studied in rat liver and heart particulate fractions. Thyroidectomy (Tx) increased isoproterenol-stimulated cAMP accumulation in the liver and decreased...

... incubated in medium 199 without serum or with 20% rat serum. Explants of rat kidney, liver or lactating mammary gland were added to some of the flasks containing the PRL in the different media. In general, the secreted PRL was found to be more readily immunoinactivated than was the purified hormone...

... and the treated females, all of which had persistent vaginal estrus. Therefore, it appears that treatment of male neonates with these weak estrogenic compounds antagonizes the androgen-mediated expression of the DHA-16α-hydroxylase activity in liver. 25 11 2008 © 1976 S. Karger AG, Basel 1976...

...Brian K. Singletary; Jay R. Zdunek; David H. Van Thiel; Patricia K. Eagon Previous work in our laboratory has defined two estrogen binders in male rat liver cytosol, one a putative estrogen receptor found in both sexes, and the other a species unique to the male. We tested other tissues of male...

...H. Rajaniemi; T. Vanha-Perttula The distribution of 125 I-labeled HCG and asialo-HCG after intravenous injection was studied quantitatively and by radioautography in the luteal, liver and kidney tissue of the mouse. It was found that the disappearance rate of HCG from the blood was markedly...

...H. Rajaniemi; A. Oksanen; T. Vanha-Perttula The distribution of 125 I-labeled ovine prolactin was studied in mice and rats after an intravenous injection by using whole-body and microautoradiography. In the whole-body autoradiography the labeled hormone rapidly accumulated in liver and kidney...

...E. Montoya; E. Herrera Three days after a single injection of streptozotocin rats showed hyperglycemia, hyperketonemia and hypoinsulinemia. Body and liver weights were reduced and the concentration of DNA-P, phospholipid-P, proteins and acetyl-CoA in the liver was augmented, while the concentration...

...P. Pervanidou; P. Xekouki; C. Dacou-Voutetakis Background: Liver dysfunction has been described in subjects with Turner syndrome. The mechanism involved is not known. Methods: Using appropriate methodology, we evaluated the hepatic enzymes serum glutamic-oxaloacetic transaminase, serum glutamic...

...Stanko Skrtic; Kristina Wallenius; Klara Sjögren; Olle G.P. Isaksson; Claes Ohlsson; John-Olov Jansson Background/Aims: Almost all circulating insulin-like growth factor-1 (IGF-1) is produced and secreted from the liver. However, the possible role of IGF-1 in local regulation of liver functions...