... and insulin) is presently unknown. Finally, GH produces a pronounced inhibition of adipose tissue lipoprotein lipase activity. This enzyme plays a main role for hydrolysing triglycerides in the blood circulation in the adipose tissue and then for triglyceride accumulation in adipose cells. Thus, GH inhibits...

...Salem A. Beshyah; Alec Henderson; Christopher Baynes; David Copping; William Richmond; Desmond G. Johnston Twenty-six hypopituitary patients on conventional replacement therapy were compared with 31 matched normal controls. Plasma lipoprotein lipase (LPL) and hepatic lipase (HL) activities were...

... of lipoprotein lipase activity thus reducing fat uptake in adipose tissue. Sixteen male rats were treated with placebo or EGF 150 µg/kg/day for 7 days via mini-osmotic pumps. The results demonstrate that systemic EGF treatment reduces the amount of adipose tissue, most likely due to increased lipolysis as HSL...