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Keywords: Leptin
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Journal Articles
Horm Res Paediatr (2022) 95 (6): 638–648.
Published Online: 29 November 2022
.... Alternatively, proponents of the “Energy Balance” hypothesis point to data implicating increased caloric intake, decreased caloric expenditure, gastrointestinal hormones, and microbiome changes as being critical for obesity. These two separate lines of research merged somewhat with the discovery of leptin...
Journal Articles
Horm Res Paediatr (2022) 95 (2): 137–148.
Published Online: 22 October 2021
... for pediatricians in terms of early identification. Src-homology-2 (SH2) B adapter protein 1 (SH2B1) is an important component in the leptin-melanocortin pathway and is found to play an important role in leptin and insulin signaling and therefore in the pathogenesis of obesity and diabetes. Microdeletions...
Journal Articles
Horm Res Paediatr (2022) 95 (2): 120–136.
Published Online: 15 June 2021
... and puberty is leptin and its interaction with the kisspeptin system, which is an important regulator of puberty. However, peripheral action of adipose tissue could also be involved in changes in the onset of puberty. In addition, nutritional factors, epigenetics, and endocrine-disrupting chemicals...
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Horm Res Paediatr (2018) 89 (3): 150–156.
Published Online: 10 January 2018
... compared to overweight children without ADHD. Methods: TSH, fT3, fT4, and leptin levels were analyzed in 230 children (60.9% boys, 9.3 ± 1.7 years old, 35.7% migration background). The children were divided into four groups (I = 26 overweight children with ADHD, II = 56 normal-weight children with ADHD...
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Journal Articles
Horm Res Paediatr (2016) 86 (5): 300–308.
Published Online: 23 September 2016
... for clinical assessments comprising anthropometrics and metabolic characterization [2-hour glucose tolerance test, leptin, peptide YY (PYY), neuropeptide Y (NPY), ghrelin, growth differentiation factor 15 (GDF-15), and adiponectin]. Results: The level of insulin resistance was associated with BMI-SDS (p...
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Horm Res Paediatr (2014) 81 (1): 20–24.
Published Online: 07 November 2013
... is unknown. We investigated serum leptin and plasma ghrelin levels before and 1 year after (adeno)tonsillectomy operation in children. Materials and Methods: We studied 31 patients and 29 age- and sex-matched healthy control children. Auxologic evaluation and biochemical investigations were performed before...
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Journal Articles
Horm Res Paediatr (2013) 80 (3): 213–216.
Published Online: 31 August 2013
... bariatric surgery. Case: A 15-year-old obese female (BMI 42.2) who was unresponsive to medical treatment underwent gastroplication. Hunger hormone levels (leptin, ghrelin and insulin), weight loss and eating behavior were monitored at 3, 6 and 12 months after surgery. Results: Weight loss was obtained...
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Journal Articles
Horm Res Paediatr (2013) 78 (5-6): 320–325.
Published Online: 04 September 2012
..., and nonalcoholic steatohepatitis. Leptin replacement effectively ameliorates these metabolic derangements. We report effects of leptin discontinuation and resumption in a child with acquired generalized lipodystrophy. Methods: Intermittent treatment with leptin with follow-up over 5 years. Results: Pretreatment...
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