...-anesthetized rats [Langer et al., 1980], may be considered as a component of nonshivering thermogene­ sis in conscious animals. Nevertheless, the mechanism o f this phenomenon remains to be further elucidated. References Balsam. A.: Sexton. F.C.: Increased metabolism of iodothyronines in the rat after short...

... tissues [ 1, 2 ]. Both T 4 and T 3 are inactivated by inner ring deiodination (IRD) to the metabolites 3,3′,5′-triiodothyronine (rT 3 ) and 3,3′-diiodothyronine (T 2 ). Three iodothyronine deiodinases (D1–3) are involved in the enzymatic deiodination of thyroid hormone (fig. 1 ) [ 1, 2 ]. D1...

... Insulin-like growth factor-I Iodothyronines Oestradiol Cortisol The ramified actions of growth hormone (GH) involve not only stimulation of insulin-like growth factor (IGF)-I and direct metabolic effects, but also a complex interaction with other hormonal systems. Most data, however, derive...