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Keywords: Insulin-like growth factor
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Journal Articles
Horm Res Paediatr (2022) 95 (6): 619–630.
Published Online: 29 November 2022
...Bradley S. Miller; Alan D. Rogol; Ron G. Rosenfeld The growth hormone (GH)–insulin-like growth factor (IGF) cascade is central to the regulation of growth and metabolism. This article focuses on the history of the components of the IGF system, with an emphasis on the peptide hormones, IGF-I and -II...
Journal Articles
Horm Res Paediatr (2017) 88 (3-4): 258–264.
Published Online: 09 August 2017
..., and subischial leg length were made. Bone age, insulin-like growth factor (IGF-I), and IGF binding protein 3 (IGFBP-3) were also measured. Results: This study showed an increase in height standard deviation score (SDS) for the whole group from –2.40 to –1.69 ( p < 0.05) after 1 year of rhGH treatment...
Journal Articles
Horm Res Paediatr (2017) 88 (1): 15–21.
Published Online: 19 May 2017
...Robin Miriam Bernstein The aim of this paper was to review information pertaining to the hormonal regulation of nonhuman primate growth, with specific focus on the growth hormone (GH)-insulin-like growth factor (IGF) axis and adrenal androgens. Hormones of the GH-IGF axis are consistently...
Journal Articles
Journal Articles
Horm Res Paediatr (2011) 76 (1): 27–34.
Published Online: 31 March 2011
..., Wit JM: Systemic and local regulation of the growth plate. Endocr Rev 2003;24:782–801. 2. Vaessen N, Janssen JA, Heutink P, Hofman A, Lamberts SW, Oostra BA, Pols HA, van Duijn CM: Association between genetic variation in the gene for insulin-like growth factor-1 and low birthweight. Lancet...
Journal Articles
Hormone Research (1996) 45 (Suppl. 1): 29–31.
Published Online: 10 December 2008
... Growth hormone Hypermetabolism Insulin Insulin-like growth factor Paediatric Plenary Lecture Horm Res 1996;45(suppl 1):29 31 D. N. Herndon E. J. Pierre K.N. Stokes R.E. Barrow Shriners Hospitals for Crippled Children. Bums Institute, Galveston. Texas, USA Growth Hormone Treatment for Burned...
Journal Articles
Hormone Research (1996) 45 (3-5): 167–171.
Published Online: 09 December 2008
...C.L. Coulter; V.K.M. Han The patterns of expression insulin-like growth factor-II (IGF-II) and IGF-binding protein-1 (IGFBP-1) mRNAs were compared between term human and rhesus monkey placenta using in situ hybridization histochemistry. Since IGFs and IGFBPs are paracrine factors...
Journal Articles
Hormone Research (1996) 45 (3-5): 160–166.
Published Online: 09 December 2008
...Victor K.M. Han; Douglas G. Matsell; Patric J.D. Delhanty; David J. Hill; Shunichi Shimasaki; Karen Nygard Insulin-like growth factors (IGF-I and IGF-II) are synthesized by most embryonic and fetal tissues, and regulate cellular growth and differentiation as autocrine/paracrine factors. A family...
Journal Articles
Hormone Research (1996) 45 (3-5): 172–177.
Published Online: 09 December 2008
...John E. Pintar; Joseph A. Cerro; Teresa L. Wood Gene targeting provides a direct method for introducing mutations into specific mouse loci. This approach has been used productively to demonstrate that insulin-like growth factor (IGF) peptides and receptors are required for normal prenatal growth...
Journal Articles
Hormone Research (1996) 45 (3-5): 252–257.
Published Online: 09 December 2008
...Jean-Marie Ketelslegers; Dominique Maiter; Marc Maes; Louis E. Underwood; Jean-Paul Thissen Both growth hormone (GH) and insulin-like growth factors (IGFs) associate with specific binding proteins. Besides control by hormones, these binding proteins are nutritionally regulated. The GH-binding...
Journal Articles
Hormone Research (1996) 46 (4-5): 195–201.
Published Online: 09 December 2008
...Robert C. Baxter Tumors of nonislet cell origin may overexpress insulin-like growth factor (IGF)-II leading to hypoglycemia with suppressed serum insulin levels (NICTH). Most of the serum IGF-II in NICTH patients is in precursor forms of 10-15 kD, and may be abnormally glycosylated. In NICTH, IGFs...
Journal Articles
Hormone Research (1996) 46 (4-5): 170–173.
Published Online: 09 December 2008
... variability, and the dependence upon assays with marginal concordancy. It is proposed that the evaluation of short stature is best pursued by careful auxology plus assessment of the insulin-like growth factor (IGF) axis, with particular attention to measurements of serum concentrations of IGF-I and IGF...
Journal Articles
Hormone Research (1996) 46 (Suppl. 1): 31–36.
Published Online: 09 December 2008
...M. Iwashita; Y. Kudo; Y. Yoshimura; T. Adachi; E. Katayama; Y. Takeda Insulin-like growth factor (IGF)-I and IGF-II, and their binding proteins (IGFBPs) have been demonstrated to play important roles in follicular development as intraovarian regulators. Previous studies have demonstrated...
Journal Articles
Hormone Research (1993) 40 (1-3): 95–98.
Published Online: 05 December 2008
...Erik F. Eriksen; Mustapha Kassem; Kim Brixen Growth hormone (GH) and insulin-like growth factors (IGFs) play a central role in skeletal growth and bone remodeling. In vitro, both agents display anabolic properties, and patients with acromegaly exhibit increased bone mass. Recent in vivo studies...
Journal Articles
Subject Area:
Endocrinology
Hormone Research (1994) 41 (1): 27–32.
Published Online: 05 December 2008
.... In addition, 18 children (10.9 ± 3.3 years) diagnosed to have GH deficiency by two different provocative tests were chosen as a further comparison group. Spontaneous 12-hour nocturnal GH secretion was assessed by RIA at 30-min intervals. Plasma insulin-like growth factor 1 (IGF-1) levels were determined...
Journal Articles
Hormone Research (1993) 39 (Suppl. 2): 37–41.
Published Online: 03 December 2008
.... Plasma insulin-like growth factor 1 levels were elevated and no remarkable advances in bone age were observed. There were no other significant changes in physical or laboratory parameters. No glucose intolerance was observed. These results indicate that GH treatment is useful for accelerating growth...
Journal Articles
Hormone Research (1992) 38 (Suppl. 1): 76–78.
Published Online: 03 December 2008
... supplementation Growth hormone Insulin-like growth factor Prostaglandins Horm Res 1992;38(suppl 1):76 78 Jean Louis Bresson Jacques Schm itz Laboratoire de Nutrition et Département de Pédiatrie. Hôpital des Enfants Malades. Paris, France Malnutrition in Crohn's Disease: Substrate Deficiency or Misuse? Key...
Journal Articles
Hormone Research (1992) 38 (Suppl. 1): 50–55.
Published Online: 03 December 2008
... to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Acromegaly Acute lymphoblastic leukaemia Brain tumours Children’s cancers Computerized tomography Insulin-like growth factor Radiation-induced growth hormone deficiency...
Journal Articles
Hormone Research (1992) 38 (1-2): 41–45.
Published Online: 03 December 2008
... that insulin could interfere with the local insulin-like growth factor systems in ovaries, and presumably in adrenals and in the hypothalamic pituitary system. The female puberty system offers a physiological model to explain the gonadotropic action of insulin. In patients with IR, HI could induce a state...
Journal Articles