... to the semisynthetic formulation at the injected subcutaneous site might have antigenicity. An H 1 histamine blocker markedly diminished the skin reaction to insulin, and her plasma glucose and glycosylated hemoglobin A Ic became well controlled. In summary, we experienced a diabetic patient with human insulin allergy...

...Jacques Beltrand; Sophie Guilmin-Crepon; Mireille Castanet; Michel Peuchmaur; Paul Czernichow; Claire Levy-Marchal Insulin allergy and lipoatrophy in type 1 diabetic patients have been previously reported but the mechanisms are not well documented. Here, we report a case emphasizing the role...