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Keywords: IGF-I
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Journal Articles
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Horm Res Paediatr (2017) 88 (5): 354–363.
Published Online: 19 September 2017
... the following: standard deviation score (SDS) values of IGF-I, IGFBP-3, and IGF-I/IGFBP-3 molar ratio before, at the 1st and at the 2nd year on rhGH and Δheight (Ht)-SDS to evaluate GH treatment efficacy (adequate 1st-year ΔHt SDS: >0.4 SDS for GHD and >0.3 SDS for non-GHD). Results: Seventy-eight percent...
Journal Articles
Horm Res Paediatr (2012) 77 (6): 341–350.
Published Online: 22 June 2012
... associations between polymorphisms in the promoter regions of IGF1 (wild type 192 bp), IGFBP3 (rs2854744; rs13241830), and INS VNTR (rs689) with cord plasma levels of IGF-I, IGF-II, and IGFBP-3. Methods: We measured IGF-I, IGF-II, and IGFBP-3 concentrations in cord blood from 677 neonates and genotyped...
Journal Articles
Journal Articles
Horm Res Paediatr (2011) 76 (Suppl. 3): 18–20.
Published Online: 07 September 2011
... hormone-insulin-like growth factor (GH-IGF) axis appear to be common in children with ISS. As the only growth-promoting treatments available to children with ISS are either human GH or recombinant human IGF-I, it is plausible that measures of the GH-IGF axis or of growth factor response might be useful...
Journal Articles
Horm Res Paediatr (2011) 76 (Suppl. 1): 84–90.
Published Online: 21 July 2011
... that extends the time window of detection is based on detection of increased levels of circulating GH-responsive proteins, such as the insulin-like growth factor (IGF) axis and collagen peptides. As age and gender are the major determinants of variability for IGF-I and the collagen markers, a test based...
Journal Articles
Horm Res Paediatr (2011) 75 (1): 56–62.
Published Online: 01 October 2010
... from any ideas, methods, instructions or products referred to in the content or advertisements. Echocardiography Growth Body mass index IGF-I IGFBP-3 Growth hormone (GH) secretory status and GH therapy influence cardiac muscle mass and function [ 1 ]. More than 85% of patients...
Journal Articles
Journal Articles
Hormone Research (2009) 72 (Suppl. 1): 48–54.
Published Online: 27 November 2009
... at the skeletal muscle and whole-body level and impair growth hormone (GH) secretion and action. Conversely, GH and insulin-like growth factor I (IGF-I) are potent protein-anabolic and growth-promoting agents in vitro and in vivo. This review summarizes both the catabolic effects of GCs and the anabolic...
Journal Articles
Hormone Research (1997) 48 (Suppl. 5): 60–64.
Published Online: 06 January 2009
... and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Adults Growth hormone IGF-I Skeletal effects Horm one R e se a rch S e ssio n 2: GH, Se x Steroid s...
Journal Articles
Hormone Research (1997) 48 (Suppl. 5): 45–49.
Published Online: 06 January 2009
... also increased the expression of both IGF-I and IGF-binding protein-5 mRNA as well as the release of IGF-I from these cells. The addition of IGF-I or recombinant IGFBP-5 alone significantly increased ALP activity and type I procollagen mRNA expression. These findings indicate that GH acts directly...
Journal Articles
Hormone Research (1996) 45 (Suppl. 1): 15–18.
Published Online: 10 December 2008
... Astroglia GFAP GHRH IGF-I LHRH Oestradiol Tanycytes Testosterone Abstract Recent evidence indicates that glia may play a significant role in the link between the endocrine and nervous systems. Gonadal steroids modulate astro­ glia morphology, differentiation and gene expression in different brain areas...
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Journal Articles
Hormone Research (1996) 46 (6): 279–281.
Published Online: 09 December 2008
... determined the 24-hour integrated concentration of GH (IC-GH), GH response to provocative stimuli, IGF-I, IGF-binding protein-3 (IGF-BP3) and GH-binding protein (GH-BP) in 34 prepubertal children (25 m/9 f) 5-10 years of age, height -2.5 to 1.5 SDS and body mass index -1.5 to 1.5 SDS for age and sex. Since...
Journal Articles
Journal Articles
Hormone Research (1995) 44 (6): 253–264.
Published Online: 05 December 2008
...). There was normal progression of puberty. Mean progression of BA was 1.2 and 1.5 years/ year during the first and second year. There was no dose effect of IGF-I on growth. Weight-for-height index (WHI) and skinfold thickness were significantly correlated at start, 12 and 24 months (r = 0.83, 0.87 and 0.79). Changes...
Journal Articles
Hormone Research (1993) 40 (4): 149–155.
Published Online: 05 December 2008
... adenomas. Octreotide caused a significant decrease of GH and IGF-I levels in all the patients and no significant change in thyroid, adrenal and gonadal function. In contrast, during the therapy, the glucose response to an oral glucose tolerance test considerably increased and was delayed, while the insulin...
Journal Articles
Journal Articles