... safety data are not yet known. Growth hormone Chronic renal failure Uremia IGF 5 12 2008 © 1993 S. Karger AG, Basel 1993 Copyright / Drug Dosage / Disclaimer Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized...

... in the embryo. Biologic control may not only be exerted at the level of growth factor synthesis and receptor expression but by the sequestration and storage of growth factors by extracellular matrix molecules. In the case of insulin-like growth factors (IGFs), storage maybe mediated by attachment to specific...

...J.L. Van den Brande; M. Jansen; C.M. Hoogerbrugge; P. de Pagter-Holthuizen; S.C. van Buul-Offers; F.M.A. van Schaik; J.S. Sussenbach The primary structure of the somatomedins (SM) IGF-I and IGF-II has been known for some years. Both from isolation of the SMs from plasma and from the study of cDNAs...

...Omar Ali; Pinchas Cohen The insulin-like growth factors (IGFs) and their binding proteins (IGFBPs) are important regulators of growth and metabolism and are the key mediators of the actions of growth hormone (GH). Children born small for gestational age (SGA) have a host of medical problems...

...Stanko Skrtic; Kristina Wallenius; Klara Sjögren; Olle G.P. Isaksson; Claes Ohlsson; John-Olov Jansson Background/Aims: Almost all circulating insulin-like growth factor-1 (IGF-1) is produced and secreted from the liver. However, the possible role of IGF-1 in local regulation of liver functions...

...Matthias M. Weber; Christoph J. Auernhammer; Phillip D.K. Lee; Dieter Engelhardt; Reinhart Zachoval Introduction: The liver is the main source of serum insulin-like growth factors (IGFs) and IGF-binding proteins (IGFBPs) and the concentration of these proteins might reflect liver function. Methods...