...Rita Saroufim; Shifaa Alkotob; Erica A. Eugster Introduction: Hypothyroidism-induced rhabdomyolysis without precipitating factors is extremely rare, particularly in pediatric patients. We describe a previously healthy adolescent boy who came to our institution with vague symptoms and was found...

... abnormalities along with ectodermal structural defects. No previous reported cases demonstrated primary hypothyroidism in a matter of Sensenbrenner syndrome. Case Presentation: Herein, we report a 6-year-old girl who suffered from progressive liver failure and end-stage renal disease secondary to Sensenbrenner...

...Laura Niuro; Emmi Danner; Liisa Viikari; Jukka Kero; Hanna Huopio; Jarmo Jääskeläinen; Harri Niinikoski Introduction: Newborn screening of congenital hypothyroidism (CH) has enabled early treatment with levothyroxine (LT4), ensuring normal growth and development. The initial LT4 dose recommendation...

... as hypothyroidism was characterized as “myxoedema” in 1878 by William Ord at St. Thomas Hospital. In 1891, George Murray reported that injection of thyroid extract from sheep led to improvement in symptoms in a woman with myxedema. Thomas Kocher, who reported that patients with goiter who underwent complete...

... and adrenal insufficiency in adults post-COVID-19. We describe the first pediatric report of adrenal insufficiency and autoimmune hypothyroidism after COVID-19. Case Presentation: A 14-year-old previously healthy girl, with vitiligo, presented in shock following 1 week of fever, lethargy, diarrhea...

...), adrenal insufficiency, and hypothyroidism. Two outcome measures were analyzed in multivariate analysis: inpatient admission and PICU admission. Adjusted odds ratios with a 95% CI were calculated using binary logistic regression, along with p values after Wald χ 2 analysis. Results: 390 patients were...

... from any ideas, methods, instructions or products referred to in the content or advertisements. Childhood cancer survivor Late effect Hypothyroidism Hyperthyroidism Thyroid cancer Tyrosine kinase inhibitor Immunotherapy Risk Radiation Proton therapy Photon 131 I...

... could clarify rates of development of hypothyroidism and thyroid antibody seroconversion, and perhaps unify guidelines. This may also allow faster comparison of the cost-effectiveness of universal versus targeted thyroid antibody or function testing. Cost-effectiveness analyses can be confounded...

...Hala Tfayli; Lama Charafeddine; Hani Tamim; Joanne Saade; Rose T. Daher; Khalid Yunis Background/Aims: Preterm newborns with a very low birth weight (VLBW) of < 1,500 g have an atypical form of hypothyroidism with a delayed rise in TSH, necessitating a second newborn screening specimen...

...Panudda Srichomkwun; Osnat Admoni; Samuel Refetoff; Liat de Vries Background: Congenital hypothyroidism (CH) is a common endocrine disorder in newborns. The cause of CH is thyroid dysgenesis in 80-85% of patients. Paired box gene 8 (PAX8) is a thyroid transcription factor that plays an important...

... the frequency and risk factors for neonatal thyroid dysfunction following HSG. Methods: We studied 212 infants born to mothers who had become pregnant after undergoing HSG involving the use of ethiodized oil. Results: Five of the 212 infants tested positive during congenital hypothyroidism screening...

... to in the content or advertisements. Children Rett syndrome Thyroid function Thyroid autoimmunity Subclinical hypothyroidism Hypothyroidism Thyroid hormone Rett syndrome (RTT; OMIM 312750) is an X-linked neurodevelopmental disorder that affects almost exclusively girls [ 1 ]. It is characterized...

...Ariel Tenenbaum; Eyal Lebel; Sarah Malkiel; Yael Kastiel; Abdulsalam Abulibdeh; David Haim Zangen Background: Aberrant thyroid function is highly prevalent in Down syndrome (DS). We aimed to find whether subclinical hypothyroidism (SCH) or low-normal free T4 (FT4) are associated with a detrimental...

... development. Care must be taken so as not to induce a state of maternal hypothyroidism during pregnancy, since such a diagnosis is also associated with adverse outcomes for both mother and infant. Conclusions: Consideration should be given to routine screening of pregnant women and all women of childbearing...

..., such as by increasing the dose of antithyroid drugs. For goitrous fetal hypothyroidism leading to hydramnios, repeated intra-amniotic injections of thyroxine have been reported to decrease the size of the fetal thyroid. Results: Experience with such procedures is limited but positive. The risk that direct in utero...

... with this condition usually present in infancy or early childhood with the signs and symptoms of isolated glucocorticoid deficiency. To date, hypothyroidism has been reported as an associated feature in a few cases. The clinical findings along with MC2R genetic analysis of five Arab kindreds are described. Subjects...

...Catherine Peters; Shirley Langham; Primus-E. Mullis; Mehul T. Dattani Hepatic haemiangiomas in infancy are rare. An association with hypothyroidism has been previously reported and is believed to be secondary to the conversion of thyroxine (fT 4 ) to biologically inactive reverse triiodothyronine...

... is present), it can generally be treated in a noninvasive way by optimizing treatment of the mother. For goitrous nonimmune fetal hypothyroidism leading to hydramnios, intra-amniotic injections of thyroxine have been reported to decrease the size of the fetal thyroid. Experience with such a procedure...

... children with goiters. Three of these children were hypothyroid at the time of initial examination. Three patients (2 hypothyroid and 1 euthyroid) had thyroid scans with radioactive iodine; iodine uptake was elevated (>80%) in all 3, and in 1 the perchlorate washout test was positive. Conclusion...

... were normal. Conclusions: Thyroid hormone replacement therapy should be considered based on biological data in patients with hyperthyrotropinemia who have a homozygous R450H mutation of the TSHR gene even if they do not exhibit obvious hypothyroidism in infancy. 17 09 2007 26 06 2008 6 6...