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Keywords: Hypoglycemia
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Horm Res Paediatr 1–12.
Published Online: 21 March 2024
...Joseph I. Wolfsdorf; Terry G.J. Derks; Danielle Drachmann; Pratik Shah; Paul S. Thornton; David A. Weinstein Sick children often have a decreased appetite and experience vomiting and diarrhea; however, hypoglycemia (plasma glucose concentration ≤50 mg/dL or 2.8 mmol/L) is rare. Ketotic hypoglycemia...
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Horm Res Paediatr (2024) 97 (3): 279–298.
Published Online: 14 July 2023
...: Hyperinsulinism (HI) due to dysregulation of pancreatic beta-cell insulin secretion is the most common and most severe cause of persistent hypoglycemia in infants and children. In the 65 years since HI in children was first described, there has been a dramatic advancement in the diagnostic tools available...
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Horm Res Paediatr (2022) 95 (6): 631–637.
Published Online: 29 November 2022
...Paul S. Thornton; Charles A. Stanley; Diva D. De Leon Congenital hyperinsulinism is the most common cause of persistent hypoglycemia in neonates, infants, and children. Since the first case descriptions in the 1950s, the field has advanced significantly. It was the development of the insulin...
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Horm Res Paediatr (2022) 95 (5): 492–498.
Published Online: 11 August 2022
..., instructions or products referred to in the content or advertisements. Hyperinsulinism Beta cells Hypoglycemia Ammonia Insulin 29 06 2022 20 07 2022 11 8 2022 deleon@chop.edu National Institutes of Health (NIH) 10.13039/100000002 Activating...
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Horm Res Paediatr (2023) 96 (6): 560–572.
Published Online: 27 January 2022
... on the cognitive development of the child, most likely because salt-losing crisis and hypoglycemia can be avoided in addition to preventing the use of high doses of glucocorticoids to treat an adrenal crisis [ 24‒26 ]. For screening to be effective, a good follow-up is an essential and immediate treatment...
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Horm Res Paediatr (2021) 94 (3-4): 115–123.
Published Online: 09 July 2021
...Michal Nevo-Shenker; Shlomit Shalitin Human and experimental animal data suggest both hyperglycemia and hypoglycemia can lead to altered brain structure and neurocognitive function in type 1 diabetes (T1D). Young children with T1D are prone to extreme fluctuations in glucose levels. The overlap...
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Horm Res Paediatr (2020) 93 (5): 297–303.
Published Online: 16 November 2020
...Nicole Falzone; Jennifer Harrington Introduction: Hyperinsulinism (HI), the most common neonatal cause of persistent hypoglycemia, can be associated with prolonged hospitalizations and risk for long-term neurological sequelae. Rapid identification of transient versus persistent forms of HI...
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Journal Articles
Horm Res Paediatr (2021) 93 (6): 396–401.
Published Online: 09 October 2020
..., generally presents peri-pubertally in girls. Case: A 2.8-year-old girl was referred due to recurrent postprandial and fasting hypoglycemia. She had been born at full-term with birth weight 1.89 kg, and had developed transient neonatal diabetes. Examination showed satisfactory growth, reduced adipose tissue...
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Horm Res Paediatr (2020) 92 (5): 319–327.
Published Online: 24 March 2020
... intermittently, but this does not provide a comprehensive assessment of glycemic control and may fail to detect episodes of hypoglycemia. Objective: To determine whether Dexcom G5®, a continuous glucose monitoring system (CGMS), is an accurate and effective method for monitoring glycemic control in children...
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Horm Res Paediatr (2018) 90 (2): 138–144.
Published Online: 25 April 2018
... cortex insufficiency leading to delayed diagnosis in this case. At the age of 1 8/12 years, the boy developed a cerebral attack caused by hypoglycemia with blood glucose of 20 mg/dL at the onset of an acute gastroenteritis. The treatment regime was hydrocortisone 3-1-2 mg and fludrocortisone 0.05-0...
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Horm Res Paediatr (2018) 89 (1): 1–6.
Published Online: 17 November 2017
...Anja Ludwig; Simone Enke; Janine Heindorf; Susann Empting; Thomas Meissner; Klaus Mohnike Background: Congenital hyperinsulinism (CHI) is hallmarked by persistent hypoketotic hypoglycemia in infancy. In the majority of all patients, CHI is caused by mutations in the KATP channel genes ABCC8...
Journal Articles
Horm Res Paediatr (2016) 85 (4): 265–272.
Published Online: 17 March 2016
...Colin P. Hawkes; Adda Grimberg; Vivian E. Dzata; Diva D. De Leon Background/Aims: The evaluation of children with unexplained hypoglycemia may include a diagnostic fast. However, low growth hormone (GH) concentration during hypoglycemia is not specific to GH deficiency (GHD). The aim of this study...