... Humans Newborn • Activating ABCC8 mutations leading to neonatal diabetes mellitus impair β-cell insulin secretion. • Activating ABCC8 mutations are associated with a decrease in insulin-producing cells and an increase in glucagon-producing cells in the endocrine pancreas...

...-peptide and insulin was determined in plasma from the antecubital vein. It has been found that stimulation of the β-adrenergic receptors with isoproterenol reduces insulin removal by the human liver. This effect of isoproterenol is prevented by blockade of the β-adrenergic receptors with propranolol...

... Humans Melatonin (MLT) is the main hormone secreted by the pineal gland. It was isolated by Lerner et al. [ 1 ] as soon as 1958. A secondary source is retina, although its systemic contribution is insignificant. This compound of indole structure (N-acetyl-5-methoxy-tryptamine) comes from...