...Saartje Straetemans; Mathieu Roelants; Muriel Thomas; Raoul Rooman; Jean De Schepper Background: Comparing observed and expected growth after first-year growth hormone (GH) therapy is useful for identifying a poor growth response to GH. Aim: To generate a first-year, age-specific growth response...

...P. Bang; R. Bjerknes; J. Dahlgren; L. Dunkel; J. Gustafsson; A. Juul; B. Kriström; P. Tapanainen; V. Åberg Background: How to define poor growth response in the management of short growth hormone (GH)-treated children is controversial. Aim: Assess various criteria of poor response. Subjects...

... was to investigate whether changes in serum adiponectin levels are related to the growth response, insulin levels and insulin resistance during growth hormone (GH) treatment. Methods: The study included 94 short prepubertal children (19 girls and 75 boys). The mean age at the start of daily GH injections was 9.04...

...-term growth response to GH therapy, and final height. 22.0% of the girls tested had a subnormal (peak < 11ng/ml) and 9.7% a pathological ( < 7ng/ml) GH response. The spontaneous GH secretion showed a good correlation with the data of the provocation tests, providing no further information...

... to in the content or advertisements. Growth hormone Adult height Growth potential Growth response Gonadal function Bone development Symposium: Final Height after GH Therapy Plenary Lecture Horm Res 1995:43:122-125 M B. Ranke Growth Research Centre, University Children s Hospital. Tübingen, Germany...

.... FRG Keywords Recombinant human growth hormone Growth hormone deficiency Treatment Growth response Growth Response to Recombinant Human Growth Hormone of Mammalian Cell Origin in Prepubertal Growth Hormone- Deficient Children during the First Tw o Years of Treatment Abstract In five clinical studies...

... hormone deficiency and treatment Growth response Growth prediction Prediction models Validation It is widely recognized that the validity of a clinical prediction model should be evaluated by applying the model to an independent group of patients. This group should be selected using the same...

...Berit Kriström; Kerstin Albertsson Wikland There is a principal and qualitative difference between using regression results on data from groups of children, and using validated prediction models for individual children. Using accurate models, it is now possible to predict the growth response...

... corresponded well with actual height gain. Differences were found when the growth response of the 1st year excluding maximum GH and that of the 2nd–5th year were calculated, resulting in a significant underestimation of actual height gain (–0.63 to –1.07 cm/year). Conclusion: The mathematical prediction model...

... (n = 548) revealed, for the three principal reasons for cessation of treatment (‘near-final height’, ‘adequate height but further growth potential’, and ‘poor growth response’), that males began and ended treatment at older ages with a better auxologic situation in SDS than girls at the beginning...

... (KIGS). First-year growth response and responsiveness (n = 394) were similar to those seen in children with idiopathic GH deficiency. The growth response over 5 years (n = 152) was unaffected by the recurrence of tumour and prior tumour management, but was greater in those receiving thyroxine. Mean...