...Francisca Grob; Amy Brown; Margaret Zacharin Introduction: Neonatal hyperthyroidism, often caused by maternal Graves’ disease (GD), carries potential neurodevelopmental risks for children. Excessive thyroid hormones during fetal development are linked to neurological issues like ADHD and epilepsy...

...Meghan E. Fredette; Sabitha Sasidharan Pillai; Osama Ibrahim; Manpreet Kochhar; Travis M. Cotton; Tanya O. Rogo; Margaret D. Scheffler; Andrew J. Bauer Introduction: Agranulocytosis is a rare but serious complication of methimazole (MMI) use for Graves’ disease (GD). Treatment requires...

...Leonie T. van Hulsteijn; Jelmer R. Prins; Mirjam E.A. Scheffer-Rath; A.S. Paul van Trotsenburg; Thera P. Links; Robin P.F. Dullaart Introduction: Women with a current diagnosis or past history of Graves’ disease (GD) are at risk of developing fetal thyrotoxicosis (FT) during pregnancy when...

... for the development of this syndrome. Until now, Graves’ disease has only been described in the literature as the probable cause of IIH in 7 patients. This report describes the case of a young girl with Graves’ disease presenting with symptoms of intracranial hypertension (IH). Case Presentation: A 21-month-old girl...

... thyroid carcinoma (PTC) and the role of coexisting Graves’ disease in the clinical course of PTC remain uncertain in children. Case Description: We report on a Japanese girl, whose PTC rapidly grew and metastasized within 4 years. Graves’ disease was diagnosed by the presence of serum TSH receptor...

... periods. We propose a diagnostic algorithm for high-risk pregnancies in mothers with current or past hyperthyroidism related to Graves' disease, involving repeated fetal thyroid gland assessments from 20 weeks of gestation onwards and maternal serum thyroid-stimulating hormone receptor antibody (TRAb...

... cause of thyrotoxicosis in childhood, after Graves' disease (GD) [ 3 ]. Presenting signs and symptoms of Htx can be very similar to those generally observed in GD, as previously reported in a retrospective study on clinical presentation of Htx in 8 children [ 4 ]. Therefore, differential diagnosis...

...Won Kyoung Cho; Min Ho Jung; Eun-Jeong Choi; Hee-Baeg Choi; Tai-Gyu Kim; Byung-Kyu Suh Backgrounds: Data regarding genetics of Hashimoto’s disease (HD) and Graves’ disease (GD) in Korean children are lacking. Methods: 73 patients with autoimmune thyroid disease (AITD; HD 32, GD 41) were recruited...

...F. Lombardo; M.F. Messina; G. Salzano; I. Rabbone; D. Lo Presti; V. Calcaterra; T. Aversa; F. De Luca; M. Wasniewska Aims: To ascertain the prevalence of Graves’ disease (GD) in 1,323 Caucasian children with type 1 diabetes mellitus (T1DM), and to compare the course of GD in T1DM patients...

...Michel Polak; Guy Van Vliet Recent advances in fetal imaging techniques and fetal hormonology allow the identification in the fetus of thyroid function disorders that can potentially be treated in utero by giving drugs to the mother. In women with Graves’ disease (when fetal hyperthyroidism...

...Malgorzata Wasniewska; Andrea Corrias; Teresa Arrigo; Fortunato Lombardo; Mariacarolina Salerno; Alessandro Mussa; Maria Cristina Vigone; Filippo De Luca Background: The development of Graves’ disease (GD) from Hashimoto’s thyroiditis (HT) has sporadically been reported, but no data are available...

...Iwona Ben-Skowronek; Jadwiga Sierocinska-Sawa; Leszek Szewczyk; Elzbieta Korobowicz Background: Graves’ disease is the archetype for organ-specific autoimmune disorders. It is very important for our understanding of the mechanisms responsible for progression of autoimmunity. The aim of this study...

...Florentia Kaguelidou; Jean Claude Carel; Juliane Léger Graves’ disease is the most common cause of hyperthyroidism in children. Antithyroid drug (ATD) treatment is recommended as the initial treatment, leading to a marked improvement in most symptoms within 1 month of treatment initiation...

... to in the content or advertisements. Cellular trafficking Gonadotrophin Graves’ disease Receptor Thyrotrophin Horm one . R e se a rch Horm Res 1997:48(suppl 4):33 37 E-MHgrom N. de Roux n . Ghinea I. Beau H. Loosfelt B. Vannier J.F. Savouret M. Misrahi Gonadotrophin and Thyrotrophin r Fr Receptors...

...’ disease Hashimoto’s thyroiditis Autoimmunity 6 1 2009 Horm one , R e se a rch Horm Res 1997;48(suppl 4):51 54 A .P . Weetman Department of Medicine, University of Sheffield Clinical Sciences Centre, Northern General Hospital. Sheffield, UK New Aspects of Thyroid Immunity Keyw ord s Graves...

...Max Rieu; Alain Richard; Rabah Sadoudi; Jean-Louis Berrod We investigated, in 20 patients with Graves’ disease and presenting with both a surgically induced hypothyroid state and increased serum antibodies (Ab) to the TSH receptor (R) levels, the relationships between thyroid status and the serum...

...Ichiro Komiya; Nobuyuki Takasu; Takashi Yamada; Noriko Ohara; Hiromi Ootsuka; Masao Ota; Hirofumi Fukushima; Akira Sekikawa; Makoto Tominaga; Hideo Sasaki We attempted to analyze the association of hyperthyroid Graves’ disease with non-insulin-dependent diabetes mellitus (NIDDM). Forty-nine...

...G. De Rosa; A. Testa; M. Mariani; M. Purpura; D. Giacomini Graves’ disease is a polygenic disease in which the HLA cluster could play a role. The purpose of our study is to identify HLA haplotypes in a family with closely related susceptibility to Graves’ disease and foresee the risk of disease...

... in sIL-2R levels was performed in the serum of 10 patients undergoing a medical treatment for Graves’ disease. All patients received carbimazole during the study and, when necessary, L -thyroxine to compensate hypothyroidism. sIL-2R levels were measured before (M0) and after the 1st (M1), 3rd (M3...

... extremely extended interstitital fibrosis with collapsed follicles and moderate lymphocytic infiltration. Thyroid-stimulation-blocking antibody was not detected at either onset of hypothyroidism. Thus, it is possible that Graves’ disease, subacute aggravation of chronic thyroiditis and hypothyroidism...