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Keywords: Etanercept
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Journal Articles
Journal:
Hormone Research in Paediatrics
Horm Res Paediatr (2012) 77 (3): 180–187.
Published Online: 12 April 2012
... in modulation of normal bone growth has been established. Methodology: Applying RT-PCR and immunohistochemistry, expression of IL-1β and TNF-α was studied in cultured fetal (E20) rat metatarsal bones. Anakinra (500 µg/ml; IL-1 receptor antagonist) and/or etanercept (500 µg/ml; soluble TNF-α receptor) were used...
Journal Articles
Journal:
Hormone Research in Paediatrics
Horm Res Paediatr (2011) 76 (4): 278–285.
Published Online: 27 September 2011
... of these cytokines with anakinra (IL-1 receptor antagonist), etanercept (TNF-inhibitor) and/or IGF-I. The bones were measured and growth expressed as percent increase in bone length over the 7-day culture period. Results: When exposed to IL-1β plus TNF-α (10 + 10 ng/ml), bone growth was markedly suppressed (6.6...
