...Martin Tauschmann; Roque Cardona-Hernandez; Daniel J. DeSalvo; Korey Hood; Dmitry N. Laptev; Anna Lindholm Olinder; Benjamin J. Wheeler; Carmel E. Smart The International Society for Pediatric and Adolescent Diabetes (ISPAD) guidelines represent a rich repository that serves as the only...

...Torben Biester; Cari Berget; Charlotte Boughton; Laura Cudizio; Laya Ekhlaspour; Marisa E. Hilliard; Leenatha Reddy; Suzanne Sap Ngo Um; Melissa Schoelwer; Jennifer L. Sherr; Klemen Dovc The International Society for Pediatric and Adolescent Diabetes (ISPAD) guidelines represent a rich repository...

...Amanda Leonard; Isabel R. Judware; Lori L. Vanscoy; Shruti M. Paranjape; Donna Peeler; Malinda Wu; Scott M. Blackman; Peter J. Mogayzel Introduction: Cystic fibrosis-related diabetes (CFRD) is linked to worsening pulmonary function and increased mortality in people with cystic fibrosis (CF...

...An Jacobs; Paramita Cifelli; Daniel Delbeck; Nancy Elbarbary; Evelien Gevers; Zdenek Sumnik; Shenali Anne Amaratunga; Auste Pundziute Lyckå; Kristina Casteels; SWEET and DPV study group Introduction: Pigmented hypertrichosis with insulin-dependent diabetes mellitus (PHID) syndrome is a rare disease...

... 2020 and February 2021. Electronic medical record data for analysis included patient demographics, BMI percentile, inpatient hospitalization or admission to the pediatric intensive care unit (PICU), and the presence of a preexisting endocrine diagnosis such as diabetes mellitus (type 1 and type 2...

...Nicole Sheanon; Deborah Elder; Jane Khoury; Lori Casnellie; Iris Gutmark-Little; Joseph Cernich; Phillipe F. Backeljauw Introduction: Adult women with Turner syndrome (TS) have a high prevalence of diabetes and β-cell dysfunction that increases morbidity and mortality, but it is unknown...

...Leena Antikainen; Jarmo Jääskeläinen; Henrikki Nordman; Raimo Voutilainen; Hanna Huopio Background: Maternal gestational diabetes mellitus (GDM) and overweight are associated with an increased risk of obesity and the metabolic syndrome in the adult offspring. We studied the influence of maternal...

... endocrinology conditions will be necessary to justify its continued use beyond the COVID-19 pandemic. For patients with new-onset diabetes mellitus, especially those presenting in diabetic ketoacidosis (DKA) or in institutions where all new-onset diabetes education is done in an inpatient setting, teams faced...

... outcomes of patients referred with prediabetes and to determine predictors of worsening dysglycemia in youth. Study Design: This is a retrospective chart review of patients referred to our Youth Diabetes Prevention Clinic (YDPC) with laboratory tests indicating an increased risk for type 2 diabetes (T2D...

...Gregory Goodwin Background: The relatively common co-occurrence of type 1 diabetes (T1D) and celiac disease (CD) suggests these disorders share common pathogenic etiologies. Summary: T1D and CD are strongly linked to closely related high-risk human lymphocyte antigens (HLA-DR-DQ). High-risk HLA...

...Fida Bacha; Peiyao Cheng; Robin L. Gal; Craig Kollman; William V. Tamborlane; Georgeanna J. Klingensmith; Katherine Manseau; Jamie Wood; Roy W. Beck; for the Pediatric Diabetes Consortium Background/Aims: Many adolescents with type 2 diabetes (T2D) have rapid deterioration of glycemic control...

...Allison C. Sylvetsky; Najy T. Issa; Avinash Chandran; Rebecca J. Brown; Hussam J. Alamri; Gabriella Aitcheson; Mary Walter; Kristina I. Rother Background: Pigment epithelium-derived factor (PEDF) is associated with obesity and diabetes complications in adults, yet little is known about PEDF...

...Stefano Stagi; Elisabetta Lapi; Cecilia Cecchi; Francesco Chiarelli; Maria Gabriella D'Avanzo; Salvatore Seminara; Maurizio de Martino Background: In adults with Williams-Beuren syndrome (WBS), a common endocrine abnormality is type 2 diabetes mellitus (T2DM) or impaired glucose tolerance (IGT...

...F. Kamran; K.I. Rother; E. Cochran; E. Safar Zadeh; P. Gorden; R.J. Brown Background/Aims: Lipodystrophy encompasses a group of rare disorders characterized by deficiency of adipose tissue resulting in hypoleptinemia, and metabolic abnormalities including insulin resistance, diabetes, dyslipidemia...

...Mandana Moosavi; Jade Séguin; Quan Li; Constantin Polychronakos Objective: To analyze the correlation between insulin requirements of type 1 diabetic (T1D) patients and genotype at type 2 diabetes (T2D) risk loci, obtained in our genome-wide association study. Methods: From a database of detailed...

...Mingyuan Wu; Timothy J. Lyons Background: Dyslipidemia is an important risk factor for cardiovascular complications in persons with diabetes. Low-density lipoprotein-cholesterol (LDL-C) is the ‘cornerstone’ for assessment of lipoprotein-associated risk. However, LDL-C levels do not reflect...

... glycemia (p = 0.01), mean 2-hour postglucose load glycemia (p < 0.05), mean AUC for glucose (p < 0.05), and mean HOMA-IR (p < 0.05). Impaired glucose tolerance was found in 16/43 GH-treated patients (37%) and transient diabetes in 2 (5%) patients. Conclusions: GH treatment in JIA children...

... of <1 year in the 1950s. The first definitive reports of glucose intolerance or diabetes in CF are from 1955. The combination of CF and related diabetes (CFRD) has a negative impact on survival. CFRD is now the most common complication of CF (50% of the CF patients will develop diabetes by the age of 30...

...P. Froguel Many human insulin-dependent (type 1) diabetes mellitus (IDDM) genes have recently been mapped. The HLA region on chromosome 6 and the insulin gene promoter on chromosome 11p have been extensively investigated. Genome scanning of many families with several affected individuals has...

...V.K. Ramiya; N.K. Maclaren Insulin-dependent diabetes (IDD) is a chronic immune-endocrine disease in which there is a progressive destruction of insulin-secreting pancreatic β cells, caused primarily by autoreactive T cells. Many islet cell proteins including insulin, glutamic acid decarboxylase...