... investigated long-term hypothalamus-pituitary-adrenal (HPA) axis function, in a prospective childhood TBI and control cohort, using measures of cortisol/cortisone secretion (physiological and stimulated), HPA axis feedback, and exploring associations with fatigue, depression, and quality of life (QoL) outcomes...

... or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. 2021 Stress Childhood and adolescent obesity Stress biology Cortisol COVID-19...

... two separate paths in the 20th century, based on two independent yet overlapping paradigms. Proponents of the “Energy Storage” hypothesis point to data implicating monogenetic disorders, the ventromedial hypothalamus, insulin, cortisol, and the adipocyte itself in the pathogenesis of obesity...

... consequences of preterm birth. Objective: We compared serum cortisol, cortisone, and cortisol/cortisone ratio in early childhood in very-low-birthweight (VLBW) infants and term appropriate for gestational age (AGA) born infants. Methods: We included 41 VLBW infants, participating in the randomized controlled...

... to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Children Early-life stress Cortisol Catecholamines Allostasis Animal studies have shown that chronically elevated stress mediators may lead to alterations...

...Perrin C. White The interconversion of active and inactive corticosteroids – cortisol and cortisone, respectively, in humans – is modulated by isozymes of 11β-hydroxysteroid dehydrogenase (11-HSD). Studies of this process have provided crucial insights into glucocorticoid effects in a wide variety...

...Pallavi Iyer; Brittany Harrington; Jeffrey J. Fadrowski; Erica Sibinga; Ernest K. Amankwah Background: The cosyntropin stimulation study (CSS) measures the patient’s ability to adequately mount a cortisol response. Clinically, CSS results may not be used to guide hydrocortisone use. The objective...

... of cortisol production. Cortisol levels measured in scalp hair provide a marker for long-term cortisol exposure. Data regarding hair cortisol concentration (HCC) in asthmatic children with ICS therapy are scarce. The aim of this study is to compare HCC in asthmatic children under ICS treatment with a healthy...

..., instructions or products referred to in the content or advertisements. [email protected] Adults and adolescents with AN have an upregulation of the hypothalamic-pituitary-adrenal axis [ 25,26 ] with an increase in integrated cortisol concentrations and suboptimal cortisol suppression following...

...Chrisanthi Marakaki; Dimitrios T. Papadimitriou; Kleanthis Kleanthous; Anna Papadopoulou; Anastasios Papadimitriou Background/Aims: We recently showed that L -Dopa administration is a potent stimulator of cortisol secretion in children with short stature. Herein, we examined whether...

...Cristina Botelho Barra; Ivani Novato Silva; Tânia Maria Barreto Rodrigues; Jovita Lane Soares Santos; Enrico Antônio Colosimo Background: The same reference values for cortisol have been used for adults and children, but laboratory results obtained from an adult population might not be suitable...

... in short healthy children. Methods: The GST was performed in 190 children investigated for short stature. A peak cortisol >500 nmol/l was considered a normal response. In the 45 (23.7%) with subnormal response, a 250-μg ACTH test was done. Results: The rate of subnormal adrenal response to GST...

...C. Marakaki; D.T. Papadimitriou; A. Papadopoulou; A. Fretzayas; A. Papadimitriou Aims: In this study, we evaluated the diagnostic usefulness of oral L -dopa as a stimulatory agent for cortisol. Methods: In 27 short children that were evaluated for possible growth hormone deficiency (GHD...

... conditions may ‘program' key endocrine systems. A disturbance of the hypothalamic-pituitary-adrenal (HPA) axis leading to alterations in cortisol secretion in the offspring may be such a mechanism. To date, no data on cortisol levels in children conceived by intracytoplasmic sperm injection (ICSI...

... cortisol concentration was measured on the 2nd day (D2) and 9th day (D9) of life. The CG's salivary cortisol concentration was measured on the 14th day of life at the child's own home. Results: The salivary cortisol concentration levels for the EG on D2 and D9 and for the CG were 4.3151 ± 2.6492, 1.826...

... brain injury) compared to healthy controls . While total cortisol concentrations did not differ between test groups, salivary and serum-free cortisol concentrations were significantly greater in both groups of children with critical illness. Cortisol-binding globulin levels were significantly lower...

...Emin Ozkaya; Mustafa A. Nursoy; Selcuk Uzuner; Ufuk Erenberk; Erkan Çakır Aims: The objective of this study is to determine the effects of the long-term treatment with inhaled fluticasone propionate on osteocalcin, cortisol levels, and bone mineral status in children with asthma. Methods...

...-matched AGA controls) were studied. Serum cortisol, cortisone, corticosteroid-binding globulin (CBG), glucocorticoid bioactivity (GBA), aldosterone, dehydroepiandrosterone sulfate (DHEAS) and androstenedione were measured, and the free cortisol index (FCI) was calculated. Results: The mean levels...

..., weight loss, a decrease in HV and very low cortisol levels; adrenal insufficiency was confirmed and glucocorticoid therapy was initiated. Subsequent peripheral motor neuropathy, achalasia and alacrima raised the suspicion of triple A syndrome, which was confirmed by the presence of a homozygous R194X...

... weeks of gestation, we hypothesized that this enzymatic step may be rate limiting in cortisol synthesis in premature infants of less than 28 weeks postmenstrual age at birth. Methods: We measured cord, first day (D0) and median fourth day (D4) serum 17-OH-pregnenolone (17-OHPreg), 17-OH-progesterone (17...