...: Cushing’s syndrome (CS) constitutes one of the most challenging diagnostic assessments for paediatric endocrinologists. The clinical presentation of some children with exogenous obesity overlaps with those observed in hypercortisolism states. Accurate, non-invasive first-line tests are necessary to avoid...

... in children. Primary pigmented nodular adrenocortical disease (PPNAD) is a rare cause of CS, which in most cases occurs in the context of Carney complex (CNC). CNC is a rare autosomal-dominantly inherited genetic syndrome, usually due to pathogenic variants of the PRKAR1A (regulatory subunit R1A...

... commonly associated with type 1 diabetes (T1D). This study aimed to evaluate the worldwide practices and attitudes of physicians involved in pediatric diabetes care regarding diagnosing and managing CD in children with T1D. Methods: The 30-item survey was conducted between July and December 2023 aimed...

... to in the content or advertisements. 2024 Sex hormone treatment Menstrual management Contraception Children Adolescents Transition Hypothalamic-ovarian conditions Structural and functional integrity of the hypothalamic-pituitary-ovarian (HPO) hormonal axis is essential for normal pubertal...

.... 2024 Type 1 diabetes Children Adolescents Diabetes complications Clinical practices Long-term complications of type 1 diabetes (T1D), encompassing microvascular (diabetic nephropathy, retinopathy, and neuropathy) and macrovascular diseases, often manifest in adulthood...

..., instructions or products referred to in the content or advertisements. 2023 Cushing Inferior petrosal sinus sampling Pituitary Children NIH Pediatric endogenous Cushing syndrome (CS) is a rare pediatric endocrine disorder, where management is often delayed [ 1 ]. Even after...

... markers may be altered in patients with diabetes owing to early cardiovascular changes. This study aimed to determine the relationship between EFT and electrocardiographic markers in children with type 1 diabetes mellitus. Methods: Children with type 1 diabetes who were followed up at the Alexandria...

... public health problem. Experimental animal and in vitro studies suggest that the exposure to BPA and phthalates are associated to a higher risk of obesity. Objective: The objective of the study was to determine urinary excretion of bisphenol A and phthalates in obese and normal weight children. Methods...

...) and unacylated ghrelin (UAG) and the AG/UAG ratio and their association with the change in eating behavior in children with PWS, compared to healthy age-matched controls. Methods: A longitudinal study was conducted in 134 children with PWS and 157 healthy controls, from the Netherlands, France, and Belgium...

... in euthyroid adults with reduced renal function. This topic is unexplored in young people with overweight or obesity (OW/OB). Objective: The aim of this study was to evaluate the association between sensitivity to TH and mild reduced estimated glomerular filtration rate (MReGFR) in euthyroid children...

... Tseretopoulou; Diana Vitali; Michael Wajnrajch; S.Faisal Ahmed Introduction: Although there are some recommendations in the literature on the assessments that should be performed in children on recombinant human growth hormone (rhGH) therapy, the level of consensus on these measurements is not clear...

...Lucie BAZUS; Kevin Perge; Pierre Chatelain; Marc Nicolino Introduction: The management of childhood type 1 diabetes requires the active participation of parents. The aim of the present study was to describe the main characteristics of parents of children with type 1 diabetes, including objective...

... withdrawal. Salivary cortisol reflects 65% of the free circulating cortisol fraction. Saliva collection is non-invasive and child friendly. Objective: We aimed to evaluate the diagnostic accuracy of morning salivary cortisol (mSAF) to determine HPA recovery after prolonged corticosteroid therapy in children...

... Introduction: The aim of the study was to assess the differences in key parameters of type 1 diabetes (T1D) control associated with treatment and monitoring modalities including newly introduced hybrid closed-loop (HCL) algorithm in children and adolescents with T1D (CwD) using the data from the population...

... on pubertal timing. Methods: Embase, MEDLINE, and Cochrane Library databases were searched until December 2021 on randomized and non-randomized controlled studies of rhGH in children. Results: Twenty-five articles ( n = 1,433 children) were identified, describing 12 randomized and 13 non-randomized controlled...

... to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. 2023 Thyrotropin-producing pituitary adenoma Thyrotropin-secreting pituitary adenoma Somatostatin Octreotide Pituitary tumour Children Hyperthyroidism 68Ga-DOTA-TATE...

... stimulation test (GH Max ) and the body mass index-standard deviation score (BMI-SDS). However, as sample sizes were quite small, our study aimed to analyze the association between GH Max and BMI-SDS within a large cohort of 991 children. Further, we investigated other influencing factors, like test type, age...

... are rapidly reversible upon discontinuation. Safety and dosing concerns in children remain. Novel treatment options have recently become available in two rare bone diseases. Burosumab, a monoclonal antibody against FGF-23, has been approved for the treatment of children with X-linked hypophosphatemic rickets...

... number of obese children undergo genetic analysis, usually when obesity is associated with dysmorphic features. The aim of this study was to identify genomic rearrangement causing obesity. Methods: We analyzed the DNA of children and adolescents by single-nucleotide polymorphism-array (platform CytoScan...

... isomers changes during normal puberty, but there are no data in relation to vascular function. We aimed to evaluate vascular function, adiponectin, and its isomers longitudinally in peri-pubertal youth with obesity and controls. Methods: The study is a cohort longitudinal study involving 30 children...