...Mimi S. Kim; Anh Dao-Tran; Elana Davidowitz; Teresa Tseng; Vicente Gilsanz; Anna Ryabets-Lienhard; Eugene Nguyen; Mitchell E. Geffner Background/Aims: Youth with congenital adrenal hyperplasia (CAH) due to 21-hydroxylase deficiency develop cardiovascular disease (CVD) risk factors of obesity...

...), fibrinogen, active plasminogen activator inhibitor type-1 and homocysteine have been proposed as potential risk factors for atherothrombotic vascular disease [ 17,18 ]. Growth hormone deficiency Children Prepuberty Cardiovascular disease Epigenetics Metabolomics Growth hormone deficiency...

...Elizabeth B. Fudge; Cathrine Constantacos; James C. Fudge; Marsha Davenport Background/Aims: Turner syndrome (TS) is associated with increased mortality due to cardiovascular disease and a dramatically higher rate of aortic dissection. The recognition and treatment of hypertension...

...Mustafa Ali Akin; Dilek Sarici; Ali Yikilmaz; Leyla Akin; Tamer Gunes; M. Adnan Ozturk; Selim Kurtoglu Background/Aims: Congenital hypothyroidism (CH) in neonates is associated with lipid alterations that might be a risk factor for early cardiovascular disease in adult life. The aim of this study...

...S.R. Daniels Background/Aims: Cardiovascular disease is the most prominent cause of mortality worldwide. A key risk factor for atherosclerotic cardiovascular disease is the presence of dyslipidemia. Clinical approaches to evaluation and treatment of dyslipidemia in children and adolescents...

... by the fetus to undernutrition are associated with changes in the concentrations of fetal placental hormones. Persisting changes in the level of hormone secretion and tissue sensitivity may link fetal undernutrition with adult disease. Cardiovascular disease Programming Undernutrition Birth weight...

... are the simplest means. Insulin resistance Cardiovascular disease Obesity 3 12 2008 © 1992 S. Karger AG, Basel 1992 Copyright / Drug Dosage / Disclaimer Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form...

...P. Mårin; P. Björntorp The associations between cardiovascular disease (CVD), non-insulin-dependent diabetes mellitus (NIDDM) and abdominal fat distribution are well established. The most important adipose tissue depot in this context is probably the mass of intra-abdominal adipose tissue which has...

... distribution. Syndrome X is itself an atherogenic cardiovascular risk factor, which interacts with environmental and genetic factors to lead to the eventual development of the endpoint of cardiovascular disease. 3 12 2008 Cardiovascular disease Diabetes Syndrome X © 1993 S. Karger AG, Basel...

... compared with the general population has been documented. Cardiovascular disease has been suggested as a primary cause of death, whereas cancer statistics might be influenced by the number of malignancies causing the pituitary disease. Furthermore, differences in mortality rates in females and males have...

... Microalbuminuria Neuropathy Cardiovascular disease A recent analysis from the US Centers for Disease Control and Prevention estimated that among children diagnosed with diabetes at age 10 years, boys would lose, on average, 18.7 life-years and 31.0 quality-adjusted life-years (QALYs), and girls 19.0 life...

... and impaired left ventricular systolic function. Exercise capacity in patients with GHD is significantly reduced and in some severely affected individuals, dilated cardiomyopathy and heart failure has been reported. GHD has also been associated with a number of risk factors for cardiovascular disease. Altered...

... IGF-I may increase the risk of IHD in otherwise healthy subjects. Hypothetically, intrauterine programming of the GH/IGF axis may influence postnatal growth, insulin resistance and consequently the risk of cardiovascular disease. Thus IGF-I may serve as a link between fetal growth and adult-onset...

... and cardiovascular disease in late adult life. These findings have led to the ‘fetal origins’ hypothesis which proposes that fetal adaptations to an adverse intrauterine environment programme persistent physiological and metabolic changes which predispose to these diseases. The mechanisms are unknown, but evidence...

... ]. In three different tamoxifen trials, women taking the drug experienced fewer fatal myocardial infarctions than those taking placebo, and also had fewer hospital admissions for cardiovascular disease. A recent meta-analysis involving 55 randomised trials, however, showed no significant decrease...

... to be high in patients with left ventricular hypertrophy due to hypertension [ 67 ]. Thus, it may be of importance to keep IGF-I within a certain critical window in order to reduce the potential risk of cardiovascular disease. Patients with acromegaly who have high IGF-I serum levels, have...