...Juliane Sonntag; Mandy Vogel; Mandy Geserick; Felix Eckelt; Antje Körner; Friedhelm Raue; Wieland Kiess; Jürgen Kratzsch Introduction: The thyroid parafollicular hormone calcitonin (CT) shows particularly high blood levels in early childhood, a period of high bone turnover, which decrease...

...B. Conte-Devolx; N. Morlet-Barla; F. Roux; F. Sebag; J.F. Henry; P. Niccoli Aims: To determine if primary hyperparathyroidism (pHPT) per se may be responsible of hypercalcitoninemia. pHPT induces chronic hypercalcemia that should be expected to be a potential stimulatory pathway of calcitonin (CT...

... absorption by the small intestine are decreased with ageing. The age-related plasma parathormone increase enhances bone remodelling. The decrease of calcitonin secretion in the elderly is possibly related to a loss of sex steroids and calcitriol. 24-hour integrated growth hormone (GH) and insulin-like growth...

...Jean-Yves L. Reginster Several approaches may be suggested for prevention or treatment of senile osteoporosis. In elderly patients, an association of calcium and vitamin D supplementation has been shown to reduce nonvertebral fractures up to 40% over an 18-month period. Calcitonin, given...

...J.J. Body This article summarizes our main findings concerning calcitonin (CT) physiology and pathology. We have devised a simple extraction method of circulating CT that much improves assay sensitivity and specificity for the measurement of the CT monomer. Combining this extraction method...

... inhibition of osteoblasts 3 days after the initiation of IMO. The role of calcitonin (CT) was investigated in the present study. A reversible increase of serum CT levels was found after intraperitoneal calcium challenge in rats on day 4 after induction of IMO, which was thought to be a result from calcium...

...G. Saggese; S. Bertelloni; G.I. Baroncelli; A. Pelletti; U. Benedetti We conducted a longitudinal study on serum levels of peptides encoded by the calcitonin gene before conception, every month during pregnancy, and 24 h and 5 days after delivery in 26 healthy women. Only subjects fulfilling...

... (MEN II), and (2) it is sporadic or inherited and benefits from a specific and sensible marker, calcitonin; the gene responsible for the hereditary form is localized on chromosome 10. Taking into account clinical, biological, genealogical and epidemiological features of the disease as supporting one...

...A.S. Yap; R.H. Mortimer; J.M. Jacobi; J.P. Galligan; D.A. Perry-Keene; F.A. Khafagi We have conducted an open, prospective study to investigate the efficacy of a single 60 mg infusion of pamidronate as alternative therapy in 15 subjects with severe Paget’s bone disease refractory to calcitonin...

...G. Saggese; S. Bertelloni; G.I. Baroncelli; A. Abadessa; P. Macchia; U. Bottom Cerebrospinal fluid (CSF) levels of immunoreactive parathyroid hormone (iPTH) and immunoreactive calcitonin (iCT) were measured by radioimmunoassay in 23 outpatient leukemic children on maintenance chemotherapy...

...S. Tabolli; C. Valtorta; F. Bigi; S. Minisola; G.F. Mazzuoli To investigate calcitonin secretion in primary hyperparathyroidism, basal and stimulated (3 mg Ca ++ /kg body weight/10 min) immunoreactive calcitonin plasma levels were studied before parathyroidectomy. Plasma calcitonin levels were...

... calcium excretion, calcium/creatinine ratio and hydroxyproline were higher than in controls (p < 0.01, p < 0.01, p < 0.02, respectively). Basal plasma calcitonin levels were in the normal range and stimulation with calcium (3 mg/kg body weight in 10 min) showed similar calcitonin responses...

...H. Schatz; M. Daun; R. Leicht; H. Stracke; W. Saeger; J. Zierski A comparison was made with the data of 62 cases of pituitary adenoma, evaluated pre- and postoperatively, including as well the results of immunohistochemical hormone examination (also for calcitonin). Prolactin was found in 18...

...Thomas Pento The distribution of calcitonin within the pig, sheep and cow thyroid was examined by measuring the concentration of the hormone in serial sagittal and transverse 5-mm sections of whole thyroids. It was observed that calcitonin in the pig thyroid was concentrated in the anterior...

...Muhammed Husain; Robert N. Alsever; Paul Lock; Walter F. George; Fred H. Katz We describe 3 patients with metastatic medullary carcinoma of the thyroid who were treated with doxorubicin hydrochloride (Adriamycin). Serum calcitonin was measured before and after doxorubicin therapy. Doxorubicin...

...Atif M. Nakhla The stimulatory effect of calcitonin on cerebral acetylcholinesterase activity could not be observed in rats pretreated with p -chlorophenylalanine. The results suggest that the response of the enzyme activity to calcitonin is 5-hydroxytryptamine-mediated. 25 04 1979 10 10...

...G.F. Mazzuoli; A. Scarda; I. Antonozzi; G. Coen Biological assay of human plasma calcitonin extracted by oxycellulose procedure gives an overestimation of hormone titer due to the calcium content of extracts.However, in the range of the extract doses required for thebioassay, calcitonin-like...

...A.D. Care; R.F.L. Bates Factors which affect the secretion of parathyroid hormone (PTH) and calcitonin (CT) are subdivided into those which are nonspecific, those associated directly with ionic changes and those associated with changes in the intracellular concentration of cyclic AMP. Whereas PTH...

... of parathyroid hormone and calcitonin in man are reviewed and their probable role in calcium homeostasis outlined. 21 11 2008 © 1971 S. Karger AG, Basel 1971 Copyright / Drug Dosage / Disclaimer Copyright: All rights reserved. No part of this publication may be translated into other languages...

... to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Osteoporosis Bone mineral density Fracture risk Treatment Alendronate Risedronate Calcitonin Raloxifene Teriparatide Osteoporosis is a major public health...