... measurements of the leg were only done for a subset of 15 SGA (4 girls) children and 22 AGA children (10 girls). Growth hormone Small for gestational age Appropriate for gestational age Very low birth weight Body composition pQCT Bone mass Muscle mass Muscle strength Children born...

... formation, while PTH increased bone mass by increasing bone formation and suppressing osteoclast number per bone area. The result of combined intervention shows an increase in trabecular, periosteal and endocortical bone formation and suppression of bone resorption resulting in a synergistic effect...

... bone maturation and a reduced peak bone mass might account for reduced BMC and BMD. Possible pathophysiological mechanisms for reduced bone mass in both childhood- and adult-onset GH deficiency are discussed. GH treatment effects on bone metabolism include increased remodelling, with increases in BMC...

...E.F. Eriksen; B.L. Langdahl Consensus and WHO definitions of osteoporosis are provided. The pathogenesis of the disorder has genetic, hormonal and environmental influences which affect peak bone mass, perimenopausal bone loss and age-dependent bone loss. Peak bone mass is mainly genetically...

...Sarah J. Holmes; Stephen M. Shalet It is now established that adults with growth hormone (GH) deficiency, of childhood or adult onset, have reduced bone mass. GH deficiency is believed to interfere with acquisition of bone mass, although an alternative mechanism is required to explain the reduction...

...P.D. Delmas Several recent studies show that bone loss continues in the elderly, and that various regimens are still effective in the elderly to stop bone loss. Thus, diagnostic procedures for osteoporosis should be considered in elderly women, i.e. measurement of bone mass by dual energy X-ray...

... their cortical bone mass and size are reduced, the trabecular skeleton is completely preserved, and bone strength, as measured by 3-point bending, is normal. If the little mutation is moved from a B6 background to C3H by ten generations of backcrossing, body size remains approximately the same, but IGF-I serum...

... not show uniformity in their evaluation of the different data. The aim of this paper is to determine the relation between urinary catecholamines, as an expression of sympathetic activity, and bone mass among the general population. Methods: A study was made of 274 individuals (124 males and 150 females...

...Laura K. Bachrach Bone densitometry is used to assess skeletal health in clinical and research settings, with the goal of achieving reproducible measurements of bone mass that help to identify individuals predisposed to fracture. The search is now on for better methods of capturing additional...

...Stephen Shalet The development of osteoporosis, with its attendant risk of fragility fracture, is in part related to the peak bone mass (PBM) achieved in early adulthood. Adolescence is a critical time for the acquisition of bone mass, with around 40% of skeletal mass being accrued during pubertal...

..., quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Partial GHD GH insufficiency Bone mass Insulin sensitivity Impaired cardiac...

...Steven A. Abrams The natural patterns of bone mass accumulation and loss with age represent the templates of individual life cycle periods that are distinguished by marked, physiologically and genetically identifiable, changes in bone mass. During the third trimester of pregnancy, maternal calcium...

... or modeling, or all together), secondly the bone parameter which describes this process, and thirdly the reason for selecting a special device. Densitometry Bone biology Modeling, bone Remodeling, bone Osteoporosis Bone mass Bone strength The purpose of this review is to combine the knowledge...

...Laura Audí; Marta García-Ramírez; Antonio Carrascosa A genetic contribution to bone mass determination was first described in the early 70s. Elucidation of gene contribution to this has since been attempted through studies analyzing associations between bone mass acquisition and/or maintenance...