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Keywords: Bone
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Journal Articles
Horm Res Paediatr (2022) 95 (6): 579–592.
Published Online: 29 November 2022
... PHEX gene in 1997. Autosomal dominant hypophosphatemic rickets similarly led to the discovery of FGF23, a phosphate-wasting humoral factor made in bone, in 2000, revolutionizing our understanding of phosphorus metabolism. 8 08 2022 10 08 2022 29 11 2022 © 2022 S. Karger AG, Basel...
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Horm Res Paediatr (2022) 94 (9-10): 390–398.
Published Online: 21 October 2021
..., instructions or products referred to in the content or advertisements. Alkaline phosphatase Asfotase alfa Bone Encephalopathy Enzyme replacement therapy Hypophosphatasia Pyridoxine Rare diseases Vitamin B6 Morbidity and mortality in hypophosphatasia (HPP) are associated with residual...
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Horm Res Paediatr (2016) 85 (3): 147–157.
Published Online: 11 February 2016
..., hypercortisolemia, altered secretion of adipokines and appetite-regulating hormones, and low bone mineral density (BMD). Bone health is impaired subsequent to a low body mass index, decreased lean mass, and the endocrine changes described above. In addition to low areal BMD, AN is characterized by a decrease...
Journal Articles
Horm Res Paediatr (2011) 76 (Suppl. 1): 7–11.
Published Online: 21 July 2011
...Paul Baldock Background: The primary relationship affecting skeletal tissue involves the association between fat mass and bone mass. However, there is some complexity in this relationship that may be explained by endocrine and neural pathways representing direct, reciprocal signalling between fat...
Journal Articles
Horm Res Paediatr (2010) 73 (3): 161–165.
Published Online: 03 March 2010
...Anenisia C. Andrade; Jeffrey Baron; Stavros C. Manolagas; Nick J. Shaw; Gudrun A. Rappold; Malcolm D.C. Donaldson; Emma Jane Gault; Lars Sävendahl This mini review summarizes papers presented in a Joint Symposium between the Bone, Growth Plate and Turner Syndrome Working Groups of the European...
Journal Articles
Hormone Research (2009) 72 (Suppl. 1): 20–25.
Published Online: 27 November 2009
.... Juvenile idiopathic arthritis Outcome Bone Growth failure Juvenile idiopathic arthritis (JIA) is a common chronic disease and an important cause of acquired impairment and disability in children and adolescents. Research into the long-term outcome of patients with JIA has accumulated during...
Journal Articles
Hormone Research (2009) 72 (Suppl. 1): 26–29.
Published Online: 27 November 2009
...F. De Benedetti Background: Chronic inflammatory diseases in children are associated with impairment of linear growth and bone mineral accrual. In addition to poor nutrition, reduced mobility and glucocorticoid treatment, several observations in patients suggest that inflammation itself may have...
Journal Articles
Hormone Research (1996) 46 (2): 95–98.
Published Online: 09 December 2008
... of bone turnover and bone loss which are presented by androgen replacement. In the growing skeleton, androgens probably have a twofold effect. Not only neonatal androgens but also pubertal androgen secretions are needed for normal skeletal growth and modeling in order to reach full size (cortical) bone...
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Hormone Research (1991) 36 (Suppl. 1): 49–55.
Published Online: 02 December 2008
...Roger Bouillon Bone and mineral metabolism is regulated by numerous hormones and local growth factors. Growth hormone (GH), directly and/or indirectly through local IGF 1 and IGF 2 production, stimulates bone turnover as it increases osteoblast number and function. It also stimulates bone...
Journal Articles
Hormone Research (1990) 33 (Suppl. 4): 65–68.
Published Online: 02 December 2008
...E.A. van der Veen; J.C. Netelenbos Calcium uptake from the gut is increased by GH effects on vitamin D metabolism or action. Bone metabolism is stimulated by many factors, of which GH and insulin-like growth factor I (IGF-I) are only two examples. From various animal and human data, it can be shown...
Journal Articles
Hormone Research (2007) 66 (Suppl. 1): 73–78.
Published Online: 25 January 2007
...Eckhard Schoenau; Oliver Fricke Bone densitometric data are often difficult to interpret in children and adolescents because of large inter- and intraindividual variations in bone size. Here, we propose a functional approach to bone densitometry that addresses two questions. Is bone strength...
Journal Articles
Hormone Research (2005) 64 (Suppl. 2): 81–85.
Published Online: 15 November 2005
... three major areas of uncertainty: (1) Is there significant heterogeneity in the bone density response of individuals to PTH? If so, what factors are important predictors? (2) What other regimens are available for PTH use? (3) What, if anything, should the clinician do after PTH is discontinued? Answers...
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Hormone Research (2004) 62 (Suppl. 4): 23–30.
Published Online: 13 December 2004
..., decreased bone mineral density, abnormal lipid profiles, decreased cardiovascular performance, reduced lean body mass (LBM), social isolation, depressed mood and increased anxiety. Importantly, the combination of physical and psychological problems can often result in a reduced quality of life. A number...
Journal Articles
Hormone Research (2000) 54 (Suppl. 1): 36–43.
Published Online: 17 November 2004
...Harold M. Frost Multidisciplinary advances in skeletal physiology offer a new paradigm for the effects of growth hormone (GH) and other agents on bone and osteoporosis. The still-evolving Utah paradigm of skeletal physiology supplements earlier ideas with later discovered roles of the skeleton’s...
Journal Articles
Hormone Research (2000) 54 (Suppl. 1): 31–35.
Published Online: 17 November 2004
...Christian Wüster There is some evidence that bone mass is reduced in the majority of adult patients with growth hormone deficiency (GHD), suggesting that such patients have an increased risk of fractures and clinically significant osteoporosis. To date, there have been only two reports of fracture...