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Keywords: Androgens
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Horm Res Paediatr (2019) 91 (6): 416–420.
Published Online: 26 August 2019
...Walter L. Miller Congenital adrenal hyperplasia (CAH) due to steroid 21-hydroxylase deficiency (21OHD) has a worldwide incidence of 1 in 15–20,000. Affected individuals have adrenal insufficiency and androgen excess; the androgen excess begins during fetal life, typically resulting in 46,XX...
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Horm Res Paediatr (2019) 91 (4): 262–270.
Published Online: 28 June 2019
... of our patient revealed elevated 17OHP and androgen levels during the first weeks of life, but values normalized spontaneously. Genetic testing for CYP21A2 mutations was negative. Thus, it remains unsettled whether the transient 17OHP elevation in this baby was due to a drug effect. Conclusion: The HIV...
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Journal Articles
Horm Res Paediatr (2018) 90 (2): 123–127.
Published Online: 18 July 2018
..., instructions or products referred to in the content or advertisements. Androgens Treatment Development Delayed puberty in boys is defined as the absence of testicular enlargement over 4 mL after the age of 14 years or greater than 2 SD later than the population mean [ 1 ]. It is a common...
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Horm Res Paediatr (2017) 87 (4): 254–263.
Published Online: 31 March 2017
...Cornelis J. de Groot; Adriaan van den Berg; Bart E.P.B. Ballieux; Herman M. Kroon; Edmond H.H.M. Rings; Jan M. Wit; Erica L.T. van den Akker Background: Childhood obesity is associated with advanced bone age (BA). Previous studies suggest that androgens, oestrogens, sex hormone-binding globulin...
Journal Articles
Horm Res Paediatr (2016) 86 (4): 253–263.
Published Online: 12 November 2015
..., instructions or products referred to in the content or advertisements. Leydig cells Steroidogenesis Phthalates Androgens Androgens synthesized by Leydig cells (LCs) play a critical role in the development of the normal male phenotype. Two distinct populations of LCs have been identified...
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Journal Articles
Horm Res Paediatr (2011) 76 (Suppl. 1): 17–23.
Published Online: 21 July 2011
... in development of function-promoting anabolic therapies. At present, androgens and myostatin inhibitors are the two leading classes of function-promoting anabolic therapies that are the most advanced in the drug development process. However, clinical development has been slowed by vexing trial design issues...
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Hormone Research (1997) 48 (3): 95–102.
Published Online: 10 December 2008
...Ruchi Mathur; Glenn D. Braunstein Gynecomastia is common in adolescents and adults, and reflects an underlying imbalance in hormonal physiology in which there is an increase in estrogen action relative to androgen action at the breast tissue level. Most patients have persistent pubertal...
Journal Articles
Hormone Research (1996) 46 (2): 95–98.
Published Online: 09 December 2008
...Dirk Vanderschueren Androgens are needed during the entire lifespan of the male skeleton -at least in the rat. Indeed, in aged nongrowing male rats, androgens are necessary for the maintenance of skeletal integrity. In these animals, androgen deficiency results in a menopause-like acceleration...
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Hormone Research (1996) 45 (1-2): 94–98.
Published Online: 09 December 2008
...Jens O.L. Jørgensen; Nina Vahl; Tony B. Hansen; Sanne Fisker; Claus Hagen; Jens S. Christiansen The secretion of both growth hormone (GH) and androgens declines with age which may play a role in the senescent changes in body composition and organ function. Among healthy adults abdominal adiposity...
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Hormone Research (1996) 45 (3-5): 148–155.
Published Online: 09 December 2008
... resistance, which can be confused with thyrotoxicosis. By constrast, the effects of androgens are controversial. In many patients with hirsutism, SHBG concentrations are low and correlate negatively with both body mass index and fasting insulin levels. Because of the inhibitory effect of both insulin...
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Hormone Research (1995) 44 (1): 35–39.
Published Online: 05 December 2008
... acquired immunodeficiency syndrome (AIDS; group B). Controls were sick non-AIDS patients admitted to an intensive care unit (ICU) and healthy volunteers. In groups A and B and the ICU controls, there was a reduction in the excretion of adrenal androgen metabolites and a reduced ratio of 5α to 5β androgen...
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Journal Articles
Hormone Research (1995) 43 (1-3): 104–110.
Published Online: 05 December 2008
... (IGF-I) levels, and reduced adrenal androgen secretion. Insulin resistance and glucose intolerance also accompany male ageing. The mechanisms of these age-related changes are still unknown. There are preliminary results on the effects of hormonal replacement therapy in older males with mild...
Journal Articles
Hormone Research (1992) 38 (Suppl. 2): 77–81.
Published Online: 03 December 2008
..., but postnatal age must be considered when interpreting the testosterone response when HCG stimulation is used as a diagnostic test. Androgen insensitivity is also a common cause of MPH; the specific defect in androgen receptor function is currently the subject of intense study, using a combination...
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Journal Articles
Hormone Research (1992) 37 (Suppl. 3): 50–54.
Published Online: 03 December 2008
... as they are metabolized in the same way as endogenous testosterone. In addition, it appears that recommended doses for replacement therapy are lower than previously suggested. An ideal formulation of testosterone for use in androgen replacement therapy is not currently available. 3 12 2008 © 1992 S. Karger AG...
Journal Articles
Subject Area:
Endocrinology
Hormone Research (1991) 36 (3-4): 160–164.
Published Online: 02 December 2008
...C. Sultan; R. Medlej; C. Chevalier; J.M. Lobaccaro Hyperandrogenism in adolescent girls can be a troubling problem because of the difficulty in establishing a diagnosis and in prescribing appropriate therapy. Androgen excess in adolescent patients encompasses a spectrum of clinical presentations...