... improvements may require functional and behavioral training intervention [ 38 ]. © 2011 S. Karger AG, Basel Copyright / Drug Dosage / Disclaimer Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means...

...Michelangela Barbieri; Virginia Boccardi; Michela Papa; Giuseppe Paolisso Background: The process of aging is associated with progressive remodeling. The age-dependent remodeling process mainly affects anthropometrics and endocrine function, which subsequently impact metabolic factors. In some...

...M.C. Gelato Elderly individuals have four to five times the case rate of cancer, tuberculosis and herpes zoster and six to seven times the fatality rate from pneumonia compared to young adults. This may be causally related to two changes that occur with aging, i.e. decreased growth hormone (GH...

...Jens O.L. Jørgensen; Nina Vahl; Tony B. Hansen; Sanne Fisker; Claus Hagen; Jens S. Christiansen The secretion of both growth hormone (GH) and androgens declines with age which may play a role in the senescent changes in body composition and organ function. Among healthy adults abdominal adiposity...

...Yvan Touitou Biological rhythms in blood variables are now fairly well documented in young healthy adults whereas reports in elderly subjects are few for obvious reasons including the difficulty of setting up a group of elderly subjects comparable in age and social background and moreover free...

.... Questions addressing cost, benefit, dosage, safety and tolerance need to be critically addressed before GH can be considered for use in the aging. 5 12 2008 © 1993 S. Karger AG, Basel 1993 Copyright / Drug Dosage / Disclaimer Copyright: All rights reserved. No part of this publication may...

... quiescence. The amplitude and frequency of GH-secretory pulses are regulated by a complex array of external and internal stimuli including age, gender, menstrual cycle phase, pubertal status, nutrition, sleep, body composition and exercise. Changes in plasma concentrations of gonadal hormones, insulin...

... a potent metabolic effect with changes in body composition, and improvement in quality of life and physical performances. This treatment is well tolerated since the adverse effects related to fluid retention could be suppressed by dose reduction. In aging, reduction in GH secretion is considered partly...

...Charles Couet; Jacques Delarue; Thierry Constans; Fernand Lamisse Impaired glucose tolerance occurs with age. This impairment is multifactorial including a decrease in insulin-mediated glucose uptake by peripheral tissues and a delay in insulin-induced suppression of hepatic glucose output. A post...

...Andrea Giustina; Anna Rosa Bussi; Claudio Conti; Mauro Doga; Fabio Legati; Claudio Macca; Fausto Zuccato; William B. Wehrenberg The aim of our study was to investigate the effects of aging on the growth hormone (GH) response to growth hormone-releasing hormone (GHRH) alone and in combination...

...N. Suganuma; T. Kitagawa; A. Nawa; Y. Tomoda The functions of human ovary change dynamically around the menopausal period. A decrease of the number of primordial follicles and an increase of fibrous tissues are observed histologically in the aged ovary. As endocrinological aspects at menopause...

...O. Tsutsumi; Y. Taketani; T. Oka A decline in fertility, defined as the number of implantation sites, was observed in mice as they aged; the decline started at 30 weeks of age and reached a nadir by 60 weeks when no implantation was detected. Epidermal growth factor (EGF) levels...

...Tatsuo Shimada; Tetsuo Morita; Kaoruko Nagai; Fuminori Sato; Hiroyuki Mori; Gordon R. Campbell Morphological changes which take place in ovarian arteries at different ages in human and monkey, were investigated by light microscopy, transmission electron microscopy and scanning electron microscopy...

...Susan L. Greenspan; David Sparrow; John W. Rowe To determine if age-related changes in glycoprotein pituitary hormone secretion are associated with alterations in dopaminergic regulation, plasma gonadotropins and TSH were measured before and after L -dopa administration in 44 young (31–44 years...

... those observed in group 1. These data suggest that in men age-related dopaminergic alterations may underlie the defective endogenous opioid control of gonadotropin secretion. 23 07 1991 22 10 1991 2 12 2008 © 1991 S. Karger AG, Basel 1991 Copyright / Drug Dosage / Disclaimer...

...V. Coiro; M. Passeri; R. Volpi; M. Marchesi; P. Bertoni; F. Fagnoni; L. Schianchi; L. Bianconi; A. Marcato; P. Chiodera The present study was undertaken in order to assess the influence of aging on the endogenous opioid control of gonadotropin and adrenocorticotropin/cortisol secretion in man...

...Marianne J. Reymond; Alena Donda; Thérèse Lemarchand-Béraud Aging is characterized by changes in neuroendocrine/endocrine functions which are manifest in female reproductive physiology and less perceptible in other functions such as thyroid, adrenal or growth/metabolic functions. The contribution...

...P.M. Wise; N.G. Weiland; K. Scarbrough; M.A. Sortino; I.R. Cohen; G.H. Larson Changes in female reproductive function occur relatively early during the life span in many mammalian species. Therefore, this physiological system is an excellent model system in which to study the effects of age...

... Thymulin Thyroid hormones Neuroendocrinology Development Aging © 1989 S. Karger AG, Basel 1989 Copyright / Drug Dosage / Disclaimer Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic...

... to be impaired in the aging rat, since a sustained reduced hypothalamic secretion of DA is observed in spite of long-term hyperprolactinemia. 28 11 2008 © 1985 S. Karger AG, Basel 1985 Copyright / Drug Dosage / Disclaimer Copyright: All rights reserved. No part of this publication may...