... an increase in their adult height (AH) in contrast to girls who are aged 6 years or more, who show no consistent pattern of increase even with GnRHa therapy. Methods: In total, 133 girls aged 6 years or more who visited any one of the seven study centers between April 2000 and March 2020 and who met...

...Jean De Schepper; Muriel Thomas; Koen Huysentruyt; Marianne Becker; Emese Boros; Kristina Casteels; Olimpia Chivu; Kathleen De Waele; Hilde Dotremont; Philippe A. Lysy; Guy Massa; Anne-Simone Parent; Anne Rochtus; Inge Gies Introduction: A variable near adult height (NAH) outcome after growth...

...Rachel Bello; Liora Lazar; Moshe Phillip; Liat de Vries Introduction: Data on adult height (AHt) in individuals with non-classical congenital adrenal hyperplasia (NCCAH) are inconsistent. Methods: We conducted a retrospective study of 109 females diagnosed with NCCAH at age <18 years who reached...

... studies compare untreated and rhGH-treated patients up to adult height (AH). Our study highlights a growth pattern from childhood to AH in patients with SHOX haploinsufficiency and analyzes the real-world effectiveness of rhGH alone or plus GnRH analog (GnRHa). Methods: Forty-seven patients (18 untreated...

... or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Adult height Turner syndrome Growth hormone therapy Turner...

... secondary to elevation of adrenal androgens that accelerates bone maturation and might compromise adult height (AH). Objective: The aim of the study was to analyze prognostic factors affecting growth trajectory (GT) and AH in children with NCCAH. Methods: The study was a retrospective, multicentric study...

... of biologic therapy as a marker of disease severity. [email protected] 22 09 2017 7 11 2017 6 12 2017 A.M. was supported by the University of Glasgow and the Glasgow Children’s Hospital Charity. Chronic diseases Inflammatory bowel disease Adult height Inflammation...

...Avivit Brener; Rachel Bello; Yael Lebenthal; Michal Yackobovitch-Gavan; Moshe Phillip; Shlomit Shalitin Background: Childhood obesity is a major health concern. Excess adiposity during childhood affects growth and puberty. Our aim was to assess whether genetic adult height is compromised...

...Saartje Straetemans; Jean De Schepper; Muriel Thomas; Franciska Verlinde; Raoul Rooman; and the members of BESPEED Background/Aim: To validate prediction models for near final adult height (nFAH) by Ranke et al. [Horm Res Paediatr 2013;79:51-67]. Methods: Height data of 127 (82 male) idiopathic...

...), but long-term comparative data between the new and the monthly formulations are very scarce. Methods: A group of girls with idiopathic CPP (n = 13; age 7.9 ± 0.6 years) were treated from the beginning with quarterly triptorelin (11.25 mg/90 days) and followed up to the achievement of adult height (AH...

... determine the impact of rhGH therapy on adult height in children with Noonan syndrome. Methods: We searched the Cochrane Central Register of Controlled Trials, ISI Web of Science, MEDLINE, and the bibliographic references from all retrieved articles published until April 2014. Studies reporting adult/near...

... in girls with Turner syndrome (TS). Methods: Serum IGF-I, GH dose, and adult height gain (AHG) from girls participating in two Dutch and five Swedish studies on the efficacy of GH were analyzed, and the cumulative GH dose and costs were calculated for both dose adjustment methods. Additional medication...

... and parameters to estimate individual GH responsiveness have yet to be determined. Objective: Retrospective evaluation of adult height (AH) and predicted adult height at GH start (descriptive model of Ranke, Model PredAH) in early and late GH-treated German UTS patients. Subjects/Methods: 313 patients treated...

...G. Binder; M. Liebl; J. Woelfle; T. Eggermann; G. Blumenstock; R. Schweizer Aims: To compare adult heights of GH-treated and GH-untreated patients with Silver-Russell syndrome (SRS) who were epigenotyped. Methods: This was a nonrandomized retrospective study with matched controls at a single center...

...Annalisa Deodati; Emanuela Peschiaroli; Stefano Cianfarani Recombinant human growth hormone (GH) has been used to increase growth and adult height in children with idiopathic short stature (ISS) despite the lack of definitive, long-term studies of efficacy. Our aim was to systematically review all...

... and nonrandomized studies of GH treatment in children with ISS from prepubertal years to adult height or near-adult height published over the last 10 years identified six publications (none was a classic meta-analysis). Several studies showed a dose-dependent response in height outcome. Overall, the younger...

...Michael B. Ranke; Anders Lindberg; on behalf of the KIGS International Board Many children with idiopathic short stature (ISS) remain short as adults. Height can be improved permanently by growth hormone (GH) treatment, as in children with Turner syndrome or born small for gestational age. Although...

...Karoliina Wehkalampi; Katarina Päkkilä; Tiina Laine; Leo Dunkel Background/Aims: Boys with constitutional delay of growth and puberty (CDGP) with early reduction in relative height before the onset of puberty will have adult height (AH) clearly below their target height (TH). Characteristics...

...Michael B. Ranke; Anders Lindberg; on behalf of the KIGS International Board Background/Aims: There is limited information about adult height (AH) outcomes and the factors influencing outcomes of growth hormone (GH) therapy in short children born small for gestational age (SGA). Methods: AH (SDS...

...Theo C.J. Sas; Maria A.J. de Ridder; Jan M. Wit; Joost Rotteveel; Wilma Oostdijk; H. Maarten Reeser; Barto J. Otten; Sabine M.P.F. de Muinck Keizer-Schrama Aim: To investigate the effect of 2 growth hormone (GH) doses on adult height (AH) in GH deficiency (GHD). Methods: A multicenter, randomized...