... levels in the training and testing datasets. Results: Overall,306 adolescents aged 12–18 (mean age 14.96 ± 1.68) years and diabetes duration of 6.57 (±3.75) participated in this study. Numeracy skills, as assessed by the WMT but not DNT-5, predicted the HbA1c levels after adjustment for sociodemographic...

...Melanie Schirmer; Stefanie Zorn; Julia von Schnurbein; Martin Wabitsch Background: Children and adolescents with severe and/or genetic obesity require continuous care and long-term treatment due to the chronic, relapsing, and progressive nature of their disease. Understanding the molecular...

... but inferred by completion of the questionnaire. The research team would like to thank the efforts of the adolescents and young adults with diabetes and their carers who dedicated their time and lived experience expertise by contributing to our survey. We would also like to thank research partners...

...Eda Cengiz; Thomas Danne; Tariq Ahmad; Ahila Ayyavoo; David Beran; Ethel Codner; Sarah Ehtisham; Przemyslawa Jarosz-Chobot; Lucy N.W. Mungai; Sze May Ng; Megan Paterson; Leena Priyambada The International Society for Pediatric and Adolescent Diabetes (ISPAD) guidelines represent a rich repository...

... that differ among individuals and populations. This chapter builds on the 2022 ISPAD guidelines and summarizes recent advances in the management of T2D in children and adolescents. Updates include diagnostic algorithm for youth with new onset T2D, algorithms and tables for treatment, management...

... physical and psychological burden. Little is known about the effects of pituitary and ovarian iron contents on ovarian reserve and function. Hence, this study aimed to assess ovarian reserve and pituitary-gonadal axis function in adolescent females with TDT and correlate them with pituitary and ovarian...

... to in the content or advertisements. 2024 Sex hormone treatment Menstrual management Contraception Children Adolescents Transition Hypothalamic-ovarian conditions Structural and functional integrity of the hypothalamic-pituitary-ovarian (HPO) hormonal axis is essential for normal pubertal...

.... 2024 Type 1 diabetes Children Adolescents Diabetes complications Clinical practices Long-term complications of type 1 diabetes (T1D), encompassing microvascular (diabetic nephropathy, retinopathy, and neuropathy) and macrovascular diseases, often manifest in adulthood...

... the mainstay strategy for obesity prevention and management. However, there remains a subset of children and adolescents whose obesity is resistant to lifestyle approach. For these poor responders, the need for safe and effective weight-reducing agents is apparent. The purpose of this review is to provide...

...Nida Gulderen Kalay Senturk; Aydilek Dagdeviren Cakir; Zeynep Yildiz Yildirmak; Ahmet Ucar Objective: Spexin (SPX) is a novel peptide implicated in food intake and satiety. SPX levels are reduced in obese patients. Aim: This study aimed to compare serum SPX levels in obese adolescents versus...

... number of obese children undergo genetic analysis, usually when obesity is associated with dysmorphic features. The aim of this study was to identify genomic rearrangement causing obesity. Methods: We analyzed the DNA of children and adolescents by single-nucleotide polymorphism-array (platform CytoScan...

... females of reproductive age. The characteristic features of PCOS individually have opposing effects on bone mineral density (BMD); however, their cumulative effect on BMD has not been clearly defined. Adolescence and young adulthood span a crucial period in achieving peak bone mass. Thus, a better...

... in the literature. Based on present knowledge, the relationship between thyropathies and other forms of diabetes, such as monogenic diabetes, has not been investigated. The aim of our study was to assess the prevalence of autoimmune thyroid diseases (ATD) in children and adolescents with maturity onset diabetes...

..., concisely addresses topics related to changes in GnRHa usage in children and adolescents over the last decade. Topics related to the use of GnRHa in precocious puberty include diagnostic criteria, globally available formulations, considerations of benefit of treatment, monitoring of therapy, adverse events...

...Nicos Skordis; Gary Butler; Martine C. de Vries; Katharina Main; Sabine E. Hannema Background/Aims: Increasing numbers of children and adolescents seek medical care because they experience incongruence between their physical sex and their gender identity. Methods: The ESPE working group on gender...

... studies [ 28-32 ], including a randomized placebo-controlled trial [ 33 ]. A similar association between low vitamin D and albuminuria in children and adolescents has not yet been shown but would form the basis for evaluation of vitamin D supplementation as a potential novel therapy for DKD in children...

... lower PEDF concentrations in adolescents and young adults with T1D compared to HV and those with T2D, but this difference was no longer significant after adjustment for BMI. This result is consistent with prior studies in healthy children and children with T2D [ 5, 7, 10, 17, 20, 21 ]. While some...

... healthy tissue is characteristic of malignancy (in most thyroid carcinomas, except for follicular thyroid carcinoma). The purpose of our study was to assess the deformation of thyroid nodules and to evaluate the usefulness of elastography in predicting malignant thyroid nodules in adolescent patients...

... Anti-Müllerian hormone Adolescents Mothers with polycystic ovary syndrome Hyperandrogenism Menstrual disturbances Polycystic ovary morphology Anti-Müllerian hormone (AMH), a member of the transforming growth factor-β superfamily, plays a crucial role in the regression of the female...

...Won Kyoung Cho; Moonbae Ahn; Yeon Jin Jeon; In Ah Jung; Kyungdo Han; Shin Hee Kim; Kyoung Soon Cho; So Hyun Park; Min Ho Jung; Byung-Kyu Suh Background: We investigate the relationship between birth weight (BW) and bone mineral content (BMC) in Korean adolescents. Methods: Data were obtained from...