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Keywords: 11β-Hydroxysteroid dehydrogenase
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Journal Articles
Horm Res Paediatr (2018) 89 (5): 320–330.
Published Online: 29 May 2018
...Perrin C. White The interconversion of active and inactive corticosteroids – cortisol and cortisone, respectively, in humans – is modulated by isozymes of 11β-hydroxysteroid dehydrogenase (11-HSD). Studies of this process have provided crucial insights into glucocorticoid effects in a wide variety...
Journal Articles
Hormone Research (1990) 34 (3-4): 114–117.
Published Online: 02 December 2008
... on the congenital deficiency of the enzyme 11β-hydroxysteroid dehydrogenase (11β-OHSD; which converts cortisol to cortisone or corticosterone to 11-dehydrocorticosterone) and acquired deficiency secondary to liquorice or carbenoxolone indicate that this enzyme plays a crucial role in protecting the MR from...
Journal Articles
Journal Articles
Journal Articles
Hormone Research (2003) 59 (6): 293–296.
Published Online: 05 June 2003
...), with no significant trend of normalization. Conclusion: Following major surgery, the substantial increase in the serum cortisol:cortisone ratio – reflecting a shift in the overall set-point of 11β-hydroxysteroid dehydrogenase activity – is more sustained than the increase in serum cortisol; the increase...
Journal Articles
Hormone Research (2002) 58 (4): 172–175.
Published Online: 19 September 2002
...M. Vogeser; R. Zachoval; T.W. Felbinger; K. Jacob Background/Objectives: 11β-Hydroxysteroid dehydrogenase (11β-HSD) enzymes convert cortisol into inactive cortisone and vice versa. While 11β-HSD type 2 (mainly localized in the kidney) unidirectionally inactivates cortisol to cortisone, type I...
Journal Articles
Hormone Research (2001) 55 (5): 245–248.
Published Online: 05 December 2001
.... Alcohol Hypertension 11β-Hydroxysteroid dehydrogenase Aldosterone synthase The enzyme 11β-hydroxysteroid dehydrogenase (11β-HSD) converts cortisol to its inactive metabolite cortisone (in rodents, corticosterone and 11-dehydrocorticosterone) [ 1 ]. If the enzyme is defective, cortisol...
Journal Articles
Hormone Research (1999) 51 (4): 189–192.
Published Online: 27 August 1999
... from any ideas, methods, instructions or products referred to in the content or advertisements. Glycyrrhizin Hypertension 11β-Hydroxysteroid dehydrogenase Aldosterone synthase The enzyme 11β-hydroxysteroid dehydrogenase (11β-HSD) converts cortisol to its inactive metabolite cortisone...