Positron emission tomography (PET) with 18F-fluorodeoxy-glucose indicates metabolically active tissue. When investigating enhancing intracranial tumours, we have suggested that PET positivity might suggest an intracranial germ cell tumour (IGCT). Here, we present a case with dicentric IGCT where PET was initially discordant between the lesions and where PET then became negative despite clearly aggressive clinical behaviour. A cautionary note is introduced with respect to the interpretation of negative 18F-FDG PET when investigating enhancing intracranial lesions.

Keywords:
Positron emission tomography, Germ cell tumours, intracranial
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© 2009 S. Karger AG, Basel
2009
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