A bioassay for inhibin, based on a dose-dependent suppression of HCG-induced ovarian weight increase in intact, immature female rats, is described. The method is specific and has acceptable sensitivity and precision such that it lends itself to statistically valid quantitative assay of inhibin activity. Being a 24-hour assay, it is conveniently and rapidly performed as well as being a multiple bioassay for estimating potencies of various preparations.

Keywords:
Inhibin, Bioassay, Immature rats, HCG-primed ovaries
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© 1976 S. Karger AG, Basel
1976
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