Various chronic diseases and malnutrition cause growth failure in childhood and adolescence; following recovery, catch-up growth may occur. The extent to which growth failure can be compensated for depends on the timing, severity and duration of the growth failure, as well as on the aetiology and pathogenesis of the disease restricting growth and development. There are three types of catch-up growth. In type 1, when growth restriction ceases, growth occurs to such an extent that the height deficit is rapidly eliminated. Once the original growth curve is attained, growth proceeds normally. In type 2, when growth restriction ceases, there is a delay in growth and somatic development. However, growth continues for longer than usual, compensating for the growth arrest. Type 3 is a mixture of types 1 and 2, and all three types may be complete or incomplete. Two factors make it difficult to record catch-up growth during adolescence: the large variability in timing, expression and duration of pubertal growth and somatic development, and the relationship between the measurement error and the increase in growth observed within a defined time period. To avoid data collection and analysis problems, prospective and long-term study design should be considered. Ideally, data collection should be started in the prepubertal period and continue until final adult height is reached. High technical standards and well-trained personnel should be used. A variety of parameters should be assessed to obtain different dimensions of the growth process and pubertal development. Data analysis should be related not only to chronological age, but also to biologically oriented time-scales, such as bone age, pubertal staging and age at peak height velocity.

This content is only available via PDF.
Copyright / Drug Dosage / Disclaimer
Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher.
Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.
You do not currently have access to this content.