...-inactivation process and the partial likelihood ratio test proposed by Xu et al. accounting for nonrandom X-inactivation process. Then, we performed an X chromosome-wide association study on 9,261 individuals from the population-based cohort CARTaGENE to identify susceptibility loci for lung cancer among...

... investigated for 20 years, but the development of statistical methods for detecting parent-of-origin effects on the X chromosome is relatively new. In the literature, a class of Q-XPAT-type tests are the only tests for the parent-of-origin effects for quantitative traits on the X chromosome. In this paper, we...

...Christina Loley; Andreas Ziegler; Inke R. König Objective: Genome-wide association studies have successfully elucidated the genetic background of complex diseases, but X chromosomal data have usually not been analyzed. A reason for this is that there is no consensus approach for the analysis taking...

...Wangwei Cai; Stefania Filosa; Giuseppe Martini In an effort to investigate the subtelomeric region of the X chromosome among Orientals, five DNA sites in the F8C and G6PD genes were analyzed in a sample of 46 chromosomes belonging to the Chinese Li population, an ethnic group characterized...

.... Mostaccuiolo; Garth A. Nicholson; Anna Sillén; Jonathan L. Haines Charcot-Marie-Tooth (CMT) disease is the most common form of inherited motor and sensory neuropathy. X-linked CMT (CMTX1) has been localized to the pericentric region of the X chromosome. Recently, mutations have been defined in the connexin 32...

...M. Al-Maghtheh; V. Ray; S.S. Mastana; M.D. Garralda; S.S. Bhattacharya; S.S. Papiha Four DNA probes (L754, p99-6, pERT87-l and pERT87-15) from the short arm of the human X chromosome were studied in two European (English and Spanish) and two Asiatic Indian (Maratha and Parsi) populations. All four...

... and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Leber’s hereditary optic neuroretinopathy LHON X chromosome Optic atrophy DXS7 DXS426 OTC Susceptibility...

...Renu Wadhwa; Surinder Papiha; Douglas Lester; Vijay Ray; N. Saha; Shomi Bhattacharya Restriction fragment length polymorphisms were investigated in five racial groups using the X chromosome probes DXS9 and DXS7. The allele frequencies of these polymorphisms showed significant differences and both...

...M. Schürmann; Regina Warneke; E. Schwinger Four restriction fragment length polymorphisms, revealed by cloned arbitrary X chromosome segments (L1.28, RC8, pD2, 754) were studied in samples (50 individuals each) of a German and a Turkish population. All previously reported alleles...

...F. Lošan; M. Macek; E. Seemanová; A. Zwinger A 30-month-old girl is presented with a deletion of the X chromosome at q 22 when examined by G- and Q-banding techniques. She exhibited dystrophia, mental and motor retardation, shortened extremities, lymphoedema, frontal protrusion of the forehead...

...Mette Warburg A number of recent genetical experiments and microbiological models are directly applicable to human ophthalmogenetics. This is particularly the case in models and experiments involving X-chromosomal markers because X-chromosomal traits are well studied in the eye. The high prevalence...

...Konstantin Strauch; Max P. Baur; Thomas F. Wienker We present a recoding scheme that allows for a parametric multipoint X-chromosomal linkage analysis of dichotomous traits in the context of a computer program for autosomes that can use trait models with imprinting. Furthermore, with this scheme...

... with prostate cancer, studies have yielded few clues as to the underlying etiologic factors or molecular defects involved. Prostate cancer X chromosome Genetic susceptibility HPCX Linkage analysis We are grateful for the cooperation of and time contributed by the men with prostate cancer...