..., instructions or products referred to in the content or advertisements. 2024 Polygenic score Genetic predisposition to disease Comorbidity Software Blood pressure Cancer Since 2006, the polygenic score (PGS), sometimes known as polygenic risk score (PRS), genetic or genomic risk score (GRS...

...Veronica J. Vieland; Yungui Huang; Sang-Cheol Seok; John Burian; Umit Catalyurek; Jeffrey O’Connell; Alberto Segre; William Valentine-Cooper This paper describes the software package KELVIN, which supports the PPL (posterior probability of linkage) framework for the measurement of statistical...

...Jeremy Buhler; David Owerbach; Alejandro A. Schäffer; Marek Kimmel; Kenneth H. Gabbay We have developed software and statistical tools for linkage analysis of polygenic diseases. We use type I diabetes mellitus (insulin-dependent diabetes mellitus, IDDM) as our model system. Two susceptibility loci...

... analysis. We implemented our method in a software package LOOP_EDGE, which is available at http://mga.bionet.nsc.ru/nlru/ . Linkage analysis Likelihood Power Breaking loops Algorithm Graph theory Software Original Paper Hum Hered 2008;65:57 65 DOI: 10.1159/000108937 Received: January 12, 2007...

... the two-stage screening procedure for analyzing large data sets. We have developed software, PREST, which calculates the test statistics and performs the corresponding hypothesis tests for relationship misclassification in general outbred pedigrees. When a potential pedigree error is detected, our...