...Qi Yan; Daniel E. Weeks; Hemant K. Tiwari; Nengjun Yi; Kui Zhang; Guimin Gao; Wan-Yu Lin; Xiang-Yang Lou; Wei Chen; Nianjun Liu Objective: The kernel machine (KM) test reportedly performs well in the set-based association test of rare variants. Many studies have been conducted to measure phenotypes...

...Rémi Kazma; Niall J. Cardin; John S. Witte Objective: To determine whether accounting for gene-environment (G×E) interactions improves the power to detect associations between rare variants and a disease, we have extended three statistical methods and compared their power under various simulated...

.... Next-generation sequencing Rare variant Trend test Genetic association GWAS Allele Locus National Institutes of Health (NIH) 10.13039/100000002 Hum Hered 2012;74:172 183 DOI: 10.1159/000346824 Published online: April 11, 2013 Single-Variant and Multi-Variant Trend Tests...

...M. Abbal; F. de Paoli; M. Cuccia-Belvedere; M. Martinetti A rare variant of complement C4 was found in 2 related individuals. It has the most anodic mobility found to date, no hemolytic activity detected by the overlay technique and a Bgl II RFLP pattern very similar to that of the C4A6 type. Hum...

.... Complement Factor B Rare variant Hum Hered 1990;40:58-60 © 1990S. Karger AG. Basel 0001-5652. 90/0401-0058 S 2.75/0 A New Complement Factor B Variant (BF S075) in Japanese Hiroaki Nishimukaia , Ikuro Maruyamab, Satoshi Takenagab, Hajime Kitamurac, Kenji Mizutanid , Takaaki Shinomiyaa Department...

...K. Suzuki; H. Matsumoto A rare variant of Factor B exhibiting a mobility intermediate between BF F and BF S was described. After comparison with the mobilities of BF F and F075, this variant was designated BF F025. The allele was transmitted together with C2*C, C4A*3, and C4B*1. 2 9 2008...

...Ch. Rittner; G. Müller 562 healthy blood donors and 65 families with 149 offspring were typed for esterase D (EsD). The observed allele frequencies are in good agreement with those determined in other Caucasian populations. The rare variant EsD 3 was found in a blood donor who transmitted it to his...

... to in the content or advertisements. LDH isoenzymes Rare variant Human Heredity 22: 271-273 (1972) A B Sub-Unit Variant of Lactate Dehydrogenase in Bulgaria R. Ananthakrishnan1. L. T sacheva and H. Walter Anthropologisches Institut, Mainz, and Institute for Morphology and Anatomy. Bulgarian Academy...