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Keywords: Multi-allelic loci
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Journal Articles

A New HLA Map of Europe: Regional Genetic Variation and Its Implication for Peopling History, Disease-Association Studies and Tissue Transplantation

Available to Purchase
Subject Area:
Genetics
Alicia Sanchez-Mazas, Stéphane Buhler, José Manuel Nunes
Journal: Human Heredity
Hum Hered (2014) 76 (3-4): 162–177.
https://doi.org/10.1159/000360855
Published Online: 21 May 2014
... HLA · Population genetics · European · Caucasian · Demographic history · Genetic diversity · Human populations · Linkage disequilibrium · Multi-allelic loci · Natural selection · Population data · Phenotypic variation · HLA haplotypes · HLA-NET · EUROSTAM Abstract Objectives: HLA genes are highly...
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Journal Articles

Generating Consistent Genotypic Configurations for Multi-Allelic Loci and Large Complex Pedigrees

Available to Purchase
Subject Area:
Genetics
Simon C. Heath
Journal: Human Heredity
Hum Hered (1998) 48 (1): 1–11.
https://doi.org/10.1159/000022775
Published Online: 08 January 1998
... for multi-allelic loci). Gibbs sampling requires an initial genotypic configuration, consistent with observed data, the generation of which is not trivial with large complex pedigrees and multi-allelic loci. A method to generate feasible genotype configurations in these circumstances using a combination...
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