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Keywords: Inbreeding
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Journal Articles
Parental Consanguinity and Family History in Relation to Psoriasis and the Role of Sex: A Case-Control Study
Open AccessSubject Area:
Genetics
Journal:
Human Heredity
Hum Hered (2025) 90 (1): 1–9.
Published Online: 31 December 2024
.... A less investigated factor in the epidemiology of psoriasis is the effect of parental consanguinity (inbreeding) on psoriasis risk in the offspring. The practice of consanguineous marriages, mating among close relatives, differs around the world, with the prevalence of consanguinity being low in Europe...
Journal Articles
Contribution of Inbred Singletons to Variance Component Estimation of Heritability and Linkage
Available to PurchaseSubject Area:
Genetics
Journal:
Human Heredity
Hum Hered (2018) 83 (2): 92–99.
Published Online: 02 November 2018
... contributes relatively little to a test of heritability but can contribute substantively to a test of linkage. For small-to-moderate quantitative trait locus (QTL) effects and a level of inbreeding comparable to matings between first cousins (the preferred form of union in many human populations), an inbred...
Journal Articles
Increased Rate of Deleterious Variants in Long Runs of Homozygosity of an Inbred Population from Qatar
Available to PurchaseSubject Area:
Genetics
Massimo Mezzavilla, Diego Vozzi, Ramin Badii, Moza Khalifa Alkowari, Khalid Abdulhadi, Giorgia Girotto, Paolo Gasparini
Journal:
Human Heredity
Hum Hered (2015) 79 (1): 14–19.
Published Online: 21 February 2015
... located outside these regions, suggesting inbreeding as a possible mechanism allowing an enrichment of putatively deleterious variants at the homozygous state. [email protected] 23 06 2014 5 12 2014 21 2 2015 © 2015 S. Karger AG, Basel 2015 Copyright / Drug...
Journal Articles
Inbreeding Coefficient Estimation with Dense SNP Data: Comparison of Strategies and Application to HapMap III
Available to PurchaseSubject Area:
Genetics
Steven Gazal, Mourad Sahbatou, Hervé Perdry, Sébastien Letort, Emmanuelle Génin, Anne-Louise Leutenegger
Journal:
Human Heredity
Hum Hered (2014) 77 (1-4): 49–62.
Published Online: 29 July 2014
... carried by the parents' common ancestor. The inbreeding coefficient measures the probability of this event and increases with increasing relatedness between the parents. It is traditionally computed from the observed inbreeding loops in the genealogies and its accuracy thus depends on the depth...
Journal Articles
Investigating the Potential Effect of Consanguinity on Type 2 Diabetes Susceptibility in a Saudi Population
Available to Purchase
Journal:
Human Heredity
Hum Hered (2014) 77 (1-4): 197–206.
Published Online: 29 July 2014
... severity was assessed in patients by recording age at diagnosis. In healthy subjects, diabetes risk was studied by measuring the body mass index, fasting blood glucose (FBG) level, and waist circumference. Extended pedigrees were constructed to calculate inbreeding coefficients. To account for tribal...
Journal Articles
Population-Genetic Influences on Genomic Estimates of the Inbreeding Coefficient: A Global Perspective
Available to PurchaseSubject Area:
Genetics
Journal:
Human Heredity
Hum Hered (2014) 77 (1-4): 37–48.
Published Online: 29 July 2014
... marriage. A commonly used measure to quantify identity by descent in an individual is the inbreeding coefficient, a quantity that reflects not only consanguinity, but also other aspects of kinship in the population to which the individual belongs. Here, in populations worldwide, we examine the relationship...
Journal Articles
Could Inbred Cases Identified in GWAS Data Succeed in Detecting Rare Recessive Variants Where Affected Sib-Pairs Have Failed?
Available to PurchaseSubject Area:
Genetics
Emmanuelle Génin, Mourad Sahbatou, Steven Gazal, Marie-Claude Babron, Hervé Perdry, Anne-Louise Leutenegger
Journal:
Human Heredity
Hum Hered (2013) 74 (3-4): 142–152.
Published Online: 11 April 2013
..., quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Rare recessive variants Inbreeding Association Linkage Genome-wide...
Journal Articles
Genealogical Information and the Structure of Rural Latin-American Populations: Reality and Fantasy
Available to PurchaseSubject Area:
Genetics
Journal:
Human Heredity
Hum Hered (1996) 46 (5): 241–255.
Published Online: 03 September 2008
..., such as histories of long periods of civil war, and large pedigrees with complex paths of inheritance resulting in complex patterns of inbreeding. Genetic themes common to all three are: (1) the use of genealogical records to substantiate the property of the land or the political power of a kinship; (2...
Journal Articles
Population Studies in Northern Sweden: XII. The Haptoglobin Polymorphism
Available to PurchaseSubject Area:
Genetics
Journal:
Human Heredity
Hum Hered (1983) 33 (6): 371–376.
Published Online: 02 September 2008
... on the structure of the North-Swedish population. 2 9 2008 Hp groups Population structure Inbreeding Ethnic heterogeneity © 1983 S. Karger AG, Basel 1983 Copyright / Drug Dosage / Disclaimer Copyright: All rights reserved. No part of this publication may be translated into other languages...
Journal Articles
Mitochondrial Malic Enzyme Polymorphism among Different Ethnic Groups in Singapore
Available to PurchaseSubject Area:
Genetics
Journal:
Human Heredity
Hum Hered (1984) 34 (6): 393–395.
Published Online: 02 September 2008
... to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Mitochondrial malic enzyme Polymorphism Singapore Chinese Malays Indians Inbreeding Ethnic differences Short Communications Hum. Hered. 34: 393-395(1984) © !984 S...
Journal Articles
Effective Population Size of a Rural Village on a Large Plain (Veggiano, Padua, Italy)
Available to PurchaseSubject Area:
Genetics
Journal:
Human Heredity
Hum Hered (1992) 42 (5): 280–288.
Published Online: 02 September 2008
... geographical barriers. Wright’s treatment of isolation by distance was considered to be applicable to this case. Estimates of the non-random component of inbreeding and of the immigration rate in the past showed that, despite the deeply rural environment, the population turnover in the area was extremely rapid...
Journal Articles
Population Studies in Northern Sweden: XIII. The 6-Phosphogluconate Dehydrogenase Polymorphism
Available to PurchaseSubject Area:
Genetics
Journal:
Human Heredity
Hum Hered (1988) 38 (3): 168–173.
Published Online: 02 September 2008
... or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Population structure in northern Sweden Inbreeding Ethnic...
Journal Articles
Inbreeding Effects on Reproductive Outcome in a Sudanese Population
Available to PurchaseSubject Area:
Genetics
Journal:
Human Heredity
Hum Hered (1990) 40 (4): 208–212.
Published Online: 02 September 2008
...N. Saha; R.E. Hamad; S. Mohamed 926 women attending the Obstetrics and Gynaecology Department of the Faculty of Medicine, Khartoum, were investigated to study the inbreeding effects on reproductive profiles and morbidity of the offspring. 49.5% of the women had married their first cousins and 13.8...
Journal Articles
Family Distances and Human Lymphocyte Antigens
Available to PurchaseSubject Area:
Genetics
Journal:
Human Heredity
Hum Hered (1987) 37 (6): 359–364.
Published Online: 02 September 2008
..., instructions or products referred to in the content or advertisements. Family distances Consanguinity Inbreeding HLA Human lymphocyte antigens Hum. Hered.37: 359-364(1987) © 1987 S. Karger AG. Basel 0001-5652/87/0376-0359 S 2.75/0 Family Distances and Human Lymphocyte Antigens Maarten J. Nautaa...
Journal Articles
Factors Influencing the Frequency of Consanguineous Marriages in Japan: Marital Distance and Opportunity of Encounter
Available to PurchaseSubject Area:
Genetics
Journal:
Human Heredity
Hum Hered (1986) 36 (5): 304–309.
Published Online: 02 September 2008
...Yoko Imaizumi The inbreeding coefficients (F) were estimated according to marital distance between birthplaces and the opportunity of encounter. As for marital distance, the F-value was the highest for the shortest distance (0.00252), whereas the F-values were similar in the other distance classes...
Journal Articles
A Study of Some Blood Genetic Characteristics of Bedouin and Non-Bedouin Arabs of Jordan
Available to PurchaseSubject Area:
Genetics
Journal:
Human Heredity
Hum Hered (1986) 36 (5): 276–280.
Published Online: 02 September 2008
... Glucose 6-phosphate dehydrogenase Bedouins Inbreeding 2 9 2008 Hum. Hered. 36: 276-280(1986) © 1986 S.Karger AG. Basel 0001-5652/86/0365-0276 S 2.75/0 A Study of Some Blood Genetic Characteristics of Bedouin and Non-Bedouin Arabs of Jordan N. Sahaa. B. Banerjeeb ' Department of Physiology...
Journal Articles
Distribution of Transferrin and Group-Specific Component Subtypes among Parsis of India
Available to PurchaseSubject Area:
Genetics
Journal:
Human Heredity
Hum Hered (1987) 37 (4): 205–210.
Published Online: 02 September 2008
... of 0.0059. The frequencies of Gc alleles were found to be 0.4478 for Gc 1F , 0.3875 for Gc 1S and 0.1647 for Gc 2 . The gene frequency of Gc 1F was rather high in comparison with Iranian and Indian populations. Parsi population India Transferrin Group-specific component Subtypes Inbreeding...
Journal Articles
Inbreeding in the State of Karnataka, South India
Available to PurchaseSubject Area:
Genetics
Journal:
Human Heredity
Hum Hered (1982) 32 (1): 8–10.
Published Online: 29 August 2008
...Radha Rama Devi; Appaji Rao; A.H. Bittles The inbreeding patterns and coefficient of inbreeding (F) of 3,350 new-borns in Bangalore, Karnataka were determined. A total of 29.24% were born of consanguineous marriages, F = 0.02313. Inbreeding was most common among the Hindus: 23.56...
Journal Articles
Dermatoglyphic Traits in an Amish-Mennonite Population in Ontario
Available to PurchaseSubject Area:
Genetics
Journal:
Human Heredity
Hum Hered (1980) 30 (5): 265–270.
Published Online: 29 August 2008
...D.A. Tutton; K. Zachariah Finger- and palmprints of 63 male and 63 female Amish-Mennonites were examined for evidence of an inbreeding effect. No significant deviations were found from the general pattern seen in other populations of similar origin in terms of distribution and frequency of palmar...
Journal Articles
A Note on the Frequency of Consanguineous Marriages in Reading, England in 1972/1973
Available to PurchaseSubject Area:
Genetics
Journal:
Human Heredity
Hum Hered (1980) 30 (5): 278–285.
Published Online: 29 August 2008
... marriages were recorded. The inbreeding coefficient for the next generation is estimated to be 0.00017 from consanguineous marriages, 0.00021 from isonymy. These values are similar to those obtained from other modern Western societies. 29 8 2008 © 1980 S. Karger AG, Basel 1980 Copyright...
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